Evaluating immune system aging in lupus patients
Official title: Systemic Lupus Erythematosus and Accelerated Aging
Run by University Hospital, Bordeaux · NCT05698173 · Data updated 2026-11-12
This study is testing how aging affects the immune system in people with lupus compared to healthy individuals to better understand their health outcomes.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 75 (estimated) |
| Sponsor | University Hospital, Bordeaux Academic / other |
| Locations | 1 site (Bordeaux) |
| Status | Recruiting |
| Started | September 8, 2023 |
| Main results expected | September 2026 |
| Study ends | September 2026 |
| Registry record updated | September 4, 2025 |
| Trial ID | NCT05698173 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 to 60 who have a confirmed diagnosis of systemic lupus erythematosus.
✕Probably not a fit
Patients who are pregnant, breastfeeding, or unable to provide informed consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the phenomenon of immune system aging in patients with systemic lupus erythematosus (SLE). It aims to compare the immune aging processes in SLE patients to age-matched healthy controls, focusing on the potential acceleration of immunosenescence in this population. By collecting blood samples and assessing various disease activity markers, the study seeks to understand how aging impacts the health outcomes of SLE patients. The research is conducted at Bordeaux University Hospital with a target enrollment of 50 participants.
Why it matters
Potential benefit: If successful, this study could provide insights into the aging process in lupus patients, potentially leading to improved management strategies and better health outcomes.
How similar studies have gone: While the specific focus on immune aging in SLE is novel, similar studies have shown that understanding immunosenescence can lead to better outcomes in other chronic conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * male or female; * age between 18 and 60 years; * Lupus patient : diagnosis of systemic lupus erythematosus according to ACR or SLICC criteria; * being affiliated to health insurance; * willing to participate and to sign informed consent. Exclusion Criteria: * pregnant or breastfeeding women; * persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent
Where it's running
-
CHU de Bordeaux - Médecine Interne et Immunologie Clinique
Bordeaux, France Recruiting
Study contacts
- Principal investigator: Noemie GENSOUS, MD — University Hospital, Bordeaux
- Study coordinator: Noemie GENSOUS, MD
- Email: noemie.gensous@chu-bordeaux.fr
- Phone: (0)5 56 79 58 28
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.