Clinical trial Recruiting at 1 site Interventional Ages 18 to 60

Evaluating immune system aging in lupus patients

Official title: Systemic Lupus Erythematosus and Accelerated Aging

Run by University Hospital, Bordeaux · NCT05698173 · Data updated 2026-11-12

This study is testing how aging affects the immune system in people with lupus compared to healthy individuals to better understand their health outcomes.

Quick facts

Study typeInterventional
Ages18 Years to 60 Years
SexAll
Enrollment75 (estimated)
SponsorUniversity Hospital, Bordeaux
Academic / other
Locations1 site (Bordeaux)
StatusRecruiting
StartedSeptember 8, 2023
Main results expectedSeptember 2026
Study endsSeptember 2026
Registry record updatedSeptember 4, 2025
Trial IDNCT05698173 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 to 60 who have a confirmed diagnosis of systemic lupus erythematosus.

Probably not a fit

Patients who are pregnant, breastfeeding, or unable to provide informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the phenomenon of immune system aging in patients with systemic lupus erythematosus (SLE). It aims to compare the immune aging processes in SLE patients to age-matched healthy controls, focusing on the potential acceleration of immunosenescence in this population. By collecting blood samples and assessing various disease activity markers, the study seeks to understand how aging impacts the health outcomes of SLE patients. The research is conducted at Bordeaux University Hospital with a target enrollment of 50 participants.

Why it matters

Potential benefit: If successful, this study could provide insights into the aging process in lupus patients, potentially leading to improved management strategies and better health outcomes.

How similar studies have gone: While the specific focus on immune aging in SLE is novel, similar studies have shown that understanding immunosenescence can lead to better outcomes in other chronic conditions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* male or female;
* age between 18 and 60 years;
* Lupus patient : diagnosis of systemic lupus erythematosus according to ACR or SLICC criteria;
* being affiliated to health insurance;
* willing to participate and to sign informed consent.

Exclusion Criteria:

* pregnant or breastfeeding women;
* persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent

Where it's running

  • CHU de Bordeaux - Médecine Interne et Immunologie Clinique
    Bordeaux, France
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.