Evaluating immune system aging in lupus patients
Systemic Lupus Erythematosus and Accelerated Aging
This study is testing how aging affects the immune system in people with lupus compared to healthy individuals to better understand their health outcomes.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 75 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | University Hospital, Bordeaux Academic / other |
| Locations | 1 site (Bordeaux) |
| Trial ID | NCT05698173 on ClinicalTrials.gov |
What this trial studies
This study investigates the phenomenon of immune system aging in patients with systemic lupus erythematosus (SLE). It aims to compare the immune aging processes in SLE patients to age-matched healthy controls, focusing on the potential acceleration of immunosenescence in this population. By collecting blood samples and assessing various disease activity markers, the study seeks to understand how aging impacts the health outcomes of SLE patients. The research is conducted at Bordeaux University Hospital with a target enrollment of 50 participants.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 60 who have a confirmed diagnosis of systemic lupus erythematosus.
Not a fit: Patients who are pregnant, breastfeeding, or unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into the aging process in lupus patients, potentially leading to improved management strategies and better health outcomes.
How similar studies have performed: While the specific focus on immune aging in SLE is novel, similar studies have shown that understanding immunosenescence can lead to better outcomes in other chronic conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * male or female; * age between 18 and 60 years; * Lupus patient : diagnosis of systemic lupus erythematosus according to ACR or SLICC criteria; * being affiliated to health insurance; * willing to participate and to sign informed consent. Exclusion Criteria: * pregnant or breastfeeding women; * persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent
Where this trial is running
Bordeaux
- CHU de Bordeaux - Médecine Interne et Immunologie Clinique — Bordeaux, France (Recruiting)
Study contacts
- Principal investigator: Noemie GENSOUS, MD — University Hospital, Bordeaux
- Study coordinator: Noemie GENSOUS, MD
- Email: noemie.gensous@chu-bordeaux.fr
- Phone: (0)5 56 79 58 28
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.