Evaluating Imaging Techniques for Heart Disease in Patients with Chronic Coronary Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the diagnostic accuracy of various imaging techniques, specifically fractional flow reserve (FFR) and optical coherence tomography (OCT), in patients with chronic coronary syndrome who have intermediate coronary stenosis. It will analyze the correlation between functional indices and morphometric parameters, such as plaque type and minimal lumen area. The study will also explore how factors like age, sex, diabetes, and renal function affect these correlations. Participants will undergo both FFR and OCT examinations to provide comprehensive data on their coronary health.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years or older
* Chronic coronary syndrome defined as presence of chest pain ranked 2-3 in the Canadian Cardiovascular Society classification or positive ischemia test (exercise test, single photon emission tomography (SPECT)
* Intermediate grade coronary stenosis of 40-80% assessed visually in coronary angiography
* FFR and OCT examination of the same lesion
* The patient is willing to participate in the study and has provided a written informed consent

Exclusion Criteria:

* Acute coronary syndrome
* Proximal left main lesion
* Ostial right coronary artery lesion
* Bypass of the assessed vessel
* Contraindications for adenosine administration
* Hemodynamic instability
* Heart insufficiency in New York Heart Association (NYHA) class IV scale
* Acute renal insufficiency
* Pregnancy

Where it's running

• Medical University of Warsaw
  Warsaw, Poland Recruiting

Study contacts

• Principal investigator: Mariusz Tomaniak, MD, PhD, Assoc. Prof. — Medical University of Warsaw
• Study coordinator: Mariusz Tomaniak
• Email: mariusz.tomaniak@wum.edu.pl

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.