Evaluating if pain modulation predicts improvement in chronic low back pain treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates whether conditioned pain modulation (CPM) can predict clinical improvement in patients suffering from chronic low back pain. It focuses on the body's ability to manage pain through its descending pain pathways and examines how physical therapy may enhance this function. Participants will undergo CPM testing to assess their pain modulation capabilities before and after a standard physical therapy regimen. The goal is to determine if improvements in CPM correlate with better outcomes in pain management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* DEERS eligible
* English speaking
* Age 18-64 years
* ODI baseline ≥25%
* NPRS baseline ≥3/10
* Low back pain symptoms greater than 3 months
* Must be able to commit to at least six weeks of physical therapy interventions

Exclusion Criteria:

* Serious spinal pathology (acute fracture, active cancer, inflammation, inflammatory arthropathy)
* Low back pain symptoms radiating below the knee
* Pregnancy
* Diagnosed neurological disease including traumatic brain injury, multiple sclerosis, chronic regional pain syndrome, and fibromyalgia.
* History spinal surgery
* Currently under litigation related to low back pain
* Currently going through Medical Evaluation Board (MEB)
* Retiring or separating from the military within a year

Where it's running

• Brooke Army Medical Center
  Fort Sam Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Kyle Petrey, DPT — Bamc
• Study coordinator: Kyle R Petrey, DPT
• Email: kyle.r.petrey.mil@health.mil
• Phone: 8472742794

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.