Evaluating how well patients in Italy stick to and benefit from Inclisiran treatment for high cholesterol

Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Inclisiran in Italy - CHOLINET (CHOLesterol Italian Inclisiran NETwork)

Observational Federico II University · NCT06287177

This study looks at how well people in Italy stick to their Inclisiran treatment for high cholesterol and whether it helps them improve their health.

Quick facts

Study typeObservational
Enrollment3000 (estimated)
Ages18 Years and up
SexAll
SponsorFederico II University Academic / other
Locations1 site (Naples)
Trial IDNCT06287177 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the adherence, persistence, and efficacy of Inclisiran treatment among patients with hypercholesterolemia in Italy. By monitoring real-life patient experiences, the study seeks to gather valuable data on how well patients follow their treatment regimen and the outcomes they achieve. The study will involve patients currently receiving Inclisiran, providing insights into its effectiveness in a practical setting. The findings could help inform future treatment strategies and guidelines for managing high cholesterol.

Who should consider this trial

Good fit: Ideal candidates for this study are patients aged 18 to 80 who are currently undergoing treatment with Inclisiran.

Not a fit: Patients under 18 years or over 80 years, as well as those who refuse to participate, will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of Inclisiran's effectiveness and improve treatment adherence for patients with high cholesterol.

How similar studies have performed: While this study focuses on real-life adherence and efficacy, similar studies evaluating treatment adherence have shown promising results in other contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients under Inclisiran treatment

Exclusion Criteria:

* Age \< 18 years o \> 80 years
* Patients who refuse to participate and to sign informed consent

Where this trial is running

Naples

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hypercholesterolemia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.