Evaluating healing time effects on tooth extraction socket preservation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to assess the impact of different healing durations (3 months vs. 6 months) on the outcomes of alveolar ridge preservation in extraction sockets affected by periodontal disease. Participants will undergo tooth extraction followed by grafting with Bio-Oss Collagen® and a collagen membrane, with evaluations conducted through histological, clinical, and radiographic methods. The study seeks to determine if a shorter healing time is viable for subsequent implant placement in molar sites.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years of age or older
* ASA (American Society of Anesthesia) status I or II
* Need for molar extraction due to periodontal disease with or without chronic endodontic involvement, complying with the presentation of periodontitis stage III/IV
* Radiographic evidence of a bone dehiscence on at least one socket wall, where the height of the horizontal (suprabony) component of the defect (alveolar bone crest - cement-enamel junction) is \>50% of the corresponding root length as measured on CBCT scans prior to extraction (Ben Amara et al., 2021)
* Radiographic evidence of at least 3 mm of residual bone wall height
* Presence of at least one adjacent tooth to the extraction site
* Treatment plan must include tooth replacement with an implant-supported fixed dental prosthesis

Exclusion Criteria:

* Extraction of multiple adjacent teeth
* Acute infection associated with the tooth to be extracted or with adjacent teeth
* Current smokers (\>10 cigarettes per day)
* Uncontrolled diabetes mellitus (HbA1c \>7.0)
* Any active oral or systemic acute infections
* Currently receiving chemo- or radiotherapy or a history of radiotherapy in the head and neck area
* Diseases or medications that may compromise normal wound healing

Where it's running

• Shanghai Ninth People's Hospital
  Shanghai, China Recruiting

Study contacts

• Study coordinator: Xinbo Yu, BDS
• Email: xinboyu@proton.me
• Phone: 86+23271699

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Effect of four post-extraction socket approaches on preserving the ridge after tooth removal

  This study tests four ways to care for an extraction socket to see which best preserves the jawbone and gum after tooth removal for future implants.

  Recruiting Universidad del Desarrollo · Santiago, Santiago Metropolitan · NCT07812883

• Immediate molar implants with customized healing abutments in different socket classes

  This study tests placing an implant right after extracting a back tooth and using a custom healing cap to shape the gum from day one, in people needing posterior implants.

  Recruiting Plovdiv Medical University · Plovdiv · NCT07801573

• Use of enamel matrix derivative with immediate implants in the lower back teeth

  This trial tests whether applying enamel matrix derivative at the time of immediate mandibular molar implants helps osseointegration and healing.

  Recruiting Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07727655

• Soft tissue augmentation around dental implants using connective tissue graft or less invasive approaches

  This trial tests three ways to increase the soft tissue around a dental implant in adults with thin gums to see which method works best.

  Recruiting Misr International University · Cairo · NCT07714265

• Biodontoss and DWC dental implants and superstructures in adults needing tooth replacement

  This PMCF study tests whether BIODENTOSS and DWC dental implants and their superstructures are safe and effective for adults with tooth loss over 24 months.

  Recruiting Değirmenci Otomotiv ve Metal Endüstri A.Ş. · Konya · NCT07633665

• Temporary dental crowns and bridges using ON DENT materials

  This PMCF study tests whether ON DENT temporary crowns and bridges perform safely and survive as patients wear them while awaiting final prostheses.

  Recruiting On Dent Tibbi Malzeme Dis Protez Ith. ve Ihr. San. Ltd. Sti. · Izmir · NCT07632443

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.