Evaluating frailty as a risk factor for mortality in young patients with septic shock

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the impact of clinical frailty, measured by the Clinical Frailty Scale (CFS), on mortality rates among adult patients aged 18 to 65 years admitted to intensive care for septic shock. It will categorize patients based on their CFS scores, identifying those who are 'frail' or 'severely frail' as potential independent risk factors for mortality. Additionally, the study will explore the relationship between frailty and outcomes such as length of hospital stay, readmission rates, and quality of life. The findings aim to enhance understanding of frailty's implications in critically ill patients and improve clinical decision-making.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged ≥18 years and ≤ 65 years
* Patient admitted to intensive care - resuscitation
* Patient admitted for suspected or documented type 3 sepsis
* Presence of vasopressor amines to maintain MAP \> 65mmHg despite filling
* Lactatemia ≥ 2 mmol/L on admission.

Exclusion Criteria:

* Patient moribund on admission
* Patients with severe pre-existing dementia and/or cognitive decline, suffering from severe neurodegenerative diseases that prevent the patient from living independently at baseline, including mental illness requiring institutionalisation, including acquired or congenital mental retardation, etc.
* Pregnant women or women in labour
* Patients under guardianship or curatorship
* Patients deprived of their liberty
* Patient and/or family unable to speak or understand French.

Where it's running

• Ch Germon Et Gauthier
  Béthune, France Recruiting
• CH Boulogne sur Mer
  Boulogne-sur-Mer, France Recruiting
• CHU de Dijon
  Dijon, France Recruiting
• CH de Lens
  Lens, France Recruiting
• CHU Lille
  Lille, France Recruiting

Study contacts

• Study coordinator: Guillaume DEGOUY, Dr
• Email: gdegouy@ch-lens.fr
• Phone: 03.21.69.12.34

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.