Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating fracture risk in patients with bone metastases from cancer

Official title: Generation of Synthetic Patient Data (RAW) for Risk Evaluation of Bone Metastases Derived From Carcinoma

Run by Istituto Ortopedico Rizzoli · NCT06524843 · Data updated 2026-11-12

This study looks at medical records of cancer patients with bone metastases to see if it can find ways to predict their risk of fractures.

More Bone Metastases trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment250 (estimated)
SponsorIstituto Ortopedico Rizzoli
Academic / other
Locations1 site (Bologna, Emilia-Romagna)
StatusRecruiting
StartedSeptember 23, 2024
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedDecember 15, 2025
Trial IDNCT06524843 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older diagnosed with bone metastases from any type of carcinoma.

Probably not a fit

Patients who do not have available imaging or clinical data, or who do not meet the inclusion criteria, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study analyzes medical records, radiological imaging, and histological data of approximately 750 patients treated for bone metastases at the Rizzoli Institute from 2010 to 2022. The goal is to develop a prediction model for assessing fracture risk in these patients based on their clinical and imaging data. By reviewing historical patient information, the study aims to identify factors that contribute to fracture risk in individuals with bone metastases. This approach could enhance understanding of patient outcomes and inform clinical decision-making.

Why it matters

Potential benefit: If successful, this study could provide a reliable prediction model for fracture risk, helping to improve patient management and treatment strategies.

How similar studies have gone: While there have been studies on fracture risk in cancer patients, this specific approach of utilizing a comprehensive historical data review for prediction modeling is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Diagnosis of bone metastasis from carcinoma, regardless of the type of carcinoma, and of the number and location of the metastases
* Availability of imaging and clinical data
* Availability of at least one follow-up during the last 12 months form diagnosis

Exclusion Criteria:

* At least one inclusion creteria not met

Where it's running

  • IRCCS Istituto Ortopedico Rizzoli
    Bologna, Emilia-Romagna, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.