Evaluating exercise rehabilitation strategies for dyspnea in COVID-19 survivors
Comparison of the Two-year Efficacy of Three Exercise Rehabilitation Strategies on Dyspnea in Patients Who Presented With Secondary Respiratory Distress Syndrome Secondary to Severe COVID-19 Pneumonia
This study is testing three different exercise programs to see if they can help COVID-19 survivors who had trouble breathing feel better and improve their quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fondation Hôpital Saint-Joseph Academic / other |
| Locations | 4 sites (Argenteuil and 3 other locations) |
| Trial ID | NCT05890560 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of three different exercise rehabilitation strategies on alleviating dyspnea in patients who have experienced respiratory distress due to severe COVID-19 pneumonia. It focuses on individuals who are at least two years post-ICU discharge and have been confirmed to have had a respiratory infection caused by SARS-CoV-2. The observational study aims to gather data on the long-term effects of rehabilitation on respiratory function and quality of life in these patients.
Who should consider this trial
Good fit: Ideal candidates are French-speaking adults aged 18 and older who are more than two years post-ICU discharge after experiencing severe COVID-19 pneumonia.
Not a fit: Patients who are currently under guardianship or curatorship may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide effective rehabilitation strategies to improve breathing and overall quality of life for COVID-19 survivors suffering from dyspnea.
How similar studies have performed: While this approach is focused on a specific population, similar rehabilitation strategies have shown promise in improving outcomes for patients with respiratory distress in other contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients in the RECOVER study (NCTT04569266): * Patient ≥ 18 years old * Patient meeting the inclusion criteria for this study (see appendix 1) * Patient more than 2 years from their release from intensive care * French-speaking patient * Patient not objecting to their participation in this research Usual care patients * Patient ≥ 18 years old * Patient having presented a respiratory infection by SARS-Cov-2 confirmed biologically in the laboratory by PCR or any other commercial or public health test or diagnosed by CT scan * Patient who was under invasive mechanical ventilation during a stay in intensive care in the center of Versailles for more than 48 consecutive hours following infection by SARS-Cov-2 between 01/03/2020 and 26/01/2022 * Patient more than 2 years from their release from intensive care * French-speaking patient * Patient not objecting to their participation in this research Exclusion Criteria: * Patient under guardianship or curatorship * Patient deprived of liberty * Patient under legal protection
Where this trial is running
Argenteuil and 3 other locations
- Centre Hospitalier Victor Dupouy — Argenteuil, France (Not_yet_recruiting)
- Fondation Hôpital Saint-Joseph — Paris, France (Recruiting)
- Hôpital Cochin — Paris, France (Not_yet_recruiting)
- Centre Hospitalier André Mignot — Versailles, France (Not_yet_recruiting)
Study contacts
- Study coordinator: Christophe ROMANET
- Email: cromanet@ghpsj.fr
- Phone: 144123085
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.