Clinical trial Recruiting at 1 site Interventional Ages 18 to 40

Evaluating electrical stimulation methods after ACL reconstruction

Official title: Neuromuscular Electrical Stimulation Superimposed or Not on Voluntary Contraction After Reconstruction of the Anterior Cruciate Ligament: a Randomized Controlled Trial

Run by Federal University of Health Science of Porto Alegre · NCT06259968 · Data updated 2026-11-12

This study is testing whether combining electrical stimulation with voluntary muscle contractions helps people recover better after knee surgery compared to just using electrical stimulation alone.

Quick facts

Study typeInterventional
Ages18 Years to 40 Years
SexAll
Enrollment40 (estimated)
SponsorFederal University of Health Science of Porto Alegre
Academic / other
Locations2 sites (Veranópolis, Rio Grande do Sul and 1 other locations)
StatusRecruiting
StartedMay 1, 2024
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedApril 1, 2025
Trial IDNCT06259968 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 18 to 40 scheduled for ACL reconstruction surgery.

Probably not a fit

Patients who are unable to initiate rehabilitation within 7 days post-surgery or have related injuries that prevent partial weight-bearing may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of neuromuscular electrical stimulation (NMES) combined with voluntary contraction versus NMES alone during the first month of rehabilitation following anterior cruciate ligament reconstruction (ACLR). Forty patients will be randomly assigned to either the NMES group or the NMES+ group, both following the same rehabilitation regimen aimed at managing symptoms, controlling inflammation, reducing edema, improving joint motion, and restoring muscle function. Assessments will occur at four time points: pre-surgery, and at 2, 15, and 30 days post-surgery, focusing on maximal isometric strength of knee extensors and other secondary outcomes related to muscle atrophy and functional impairments.

Why it matters

Potential benefit: If successful, this study could enhance rehabilitation outcomes for patients recovering from ACL reconstruction.

How similar studies have gone: Previous studies have shown promise in using neuromuscular electrical stimulation for rehabilitation, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Individuals of both genders, aged between 18 and 40 years, scheduled for ACL reconstruction surgery during the data collection period.

Exclusion Criteria:

* Failure to attend the pre-surgery assessment session;
* Delay of more than 7 days after surgery to initiate the rehabilitation program proposed by the study;
* Presence of injuries related to the rupture of the ACL that hinder partial weight-bearing in the first week after surgery, either due to medical recommendation or the patient inability/disposition.

Where it's running

  • Private Rehabilitation Center
    Veranópolis, Rio Grande do Sul, Brazil
    Recruiting
  • Private Rehabilitation Center
    Veranópolis, Rio Grande do Sul, Brazil
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.