Evaluating electrical stimulation methods after ACL reconstruction
Official title: Neuromuscular Electrical Stimulation Superimposed or Not on Voluntary Contraction After Reconstruction of the Anterior Cruciate Ligament: a Randomized Controlled Trial
Run by Federal University of Health Science of Porto Alegre · NCT06259968 · Data updated 2026-11-12
This study is testing whether combining electrical stimulation with voluntary muscle contractions helps people recover better after knee surgery compared to just using electrical stimulation alone.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Federal University of Health Science of Porto Alegre Academic / other |
| Locations | 2 sites (Veranópolis, Rio Grande do Sul and 1 other locations) |
| Status | Recruiting |
| Started | May 1, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | April 1, 2025 |
| Trial ID | NCT06259968 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 18 to 40 scheduled for ACL reconstruction surgery.
✕Probably not a fit
Patients who are unable to initiate rehabilitation within 7 days post-surgery or have related injuries that prevent partial weight-bearing may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of neuromuscular electrical stimulation (NMES) combined with voluntary contraction versus NMES alone during the first month of rehabilitation following anterior cruciate ligament reconstruction (ACLR). Forty patients will be randomly assigned to either the NMES group or the NMES+ group, both following the same rehabilitation regimen aimed at managing symptoms, controlling inflammation, reducing edema, improving joint motion, and restoring muscle function. Assessments will occur at four time points: pre-surgery, and at 2, 15, and 30 days post-surgery, focusing on maximal isometric strength of knee extensors and other secondary outcomes related to muscle atrophy and functional impairments.
Why it matters
Potential benefit: If successful, this study could enhance rehabilitation outcomes for patients recovering from ACL reconstruction.
How similar studies have gone: Previous studies have shown promise in using neuromuscular electrical stimulation for rehabilitation, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Individuals of both genders, aged between 18 and 40 years, scheduled for ACL reconstruction surgery during the data collection period. Exclusion Criteria: * Failure to attend the pre-surgery assessment session; * Delay of more than 7 days after surgery to initiate the rehabilitation program proposed by the study; * Presence of injuries related to the rupture of the ACL that hinder partial weight-bearing in the first week after surgery, either due to medical recommendation or the patient inability/disposition.
Where it's running
-
Private Rehabilitation Center
Veranópolis, Rio Grande do Sul, Brazil Recruiting -
Private Rehabilitation Center
Veranópolis, Rio Grande do Sul, Brazil Not yet recruiting
Study contacts
- Study coordinator: Gabriela Bissani Gasparin
- Email: gabriela.gasparin@hotmail.com
- Phone: +5554991296689
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Eccentric training for rehabilitation after ACL surgery
This study is testing if a special type of exercise called eccentric training helps people recover better after ACL surgery compared to regular rehab exercises.
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Plyometric training added to standard rehab after ACL reconstruction
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Isokinetic vs Plyometric Training After ACL Reconstruction
This trial tests whether isokinetic or plyometric training, added after standard rehab, best improves strength, function, and patient-reported outcomes in adults 18–40 after ACL reconstruction.
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This study tests whether adding a BiFeS block to the standard adductor canal block provides better pain relief after ACL reconstruction.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.