Evaluating ECGs with Deep Learning for Athlete Health

Deep Learning ECG Evaluation and Clinical Assessment for Competitive Sport Eligibility

Observational I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · NCT06285084

This study is testing a new computer program that looks at heart scans of athletes to see if it can help determine who is healthy enough to compete in sports.

Quick facts

Study typeObservational
Enrollment531 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorI.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio Academic / other
Locations1 site (Milan, Lombardy)
Trial IDNCT06285084 on ClinicalTrials.gov

What this trial studies

This observational study aims to develop a Deep Learning model that analyzes electrocardiographic traces of athletes to assess their cardiovascular health and eligibility for competitive sports. Researchers will first train the model using data from 455 athletes, categorizing them as 'fit' or 'unfit' based on standard clinical evaluations. A subsequent validation cohort of 76 athletes will be used to test the model's accuracy in distinguishing between those cleared for sports and those requiring further medical assessment. The study follows established guidelines for sports participation and aims to enhance the safety of athletes in competitive environments.

Who should consider this trial

Good fit: Ideal candidates are athletes aged 18 to 60 who require cardiac evaluations for competitive eligibility and have no history of cardiovascular disease.

Not a fit: Patients engaged in skill-based sports or those with a high clinical probability of cardiovascular disease may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the accuracy of cardiovascular assessments for athletes, ensuring safer participation in competitive sports.

How similar studies have performed: While the use of Deep Learning in ECG analysis is emerging, this specific application for athlete eligibility is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Athletes in need of cardiac or sports medical evaluation for the issuance of competitive eligibility.
* Enlisted athletes involved in sports like soccer or those with mixed or aerobic cardiovascular demands according to the COCIS 2017 classification.
* Aged 18 years or older but not exceeding 60 years.
* No history of cardiovascular disease.
* Signed Informed Consent.

Exclusion Criteria:

* Athletes engaging in skill-based sports as per the COCIS 2017 classification.
* High clinical probability of cardiovascular disease, such as typical angina or heart failure.
* Pregnancy and/or breastfeeding (confirmed through self-declaration).

Where this trial is running

Milan, Lombardy

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Sports CardiologyPreventive CardiologyElectrocardiogramArtificial Intelligence
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.