Evaluating early mobilization and rehabilitation for ICU patients

Feasibility and Safety of Early Mobilization and Rehabilitation in Intensive Care Unit Patients. A Prospective, Multicenter Study

Observational Sanitas University · NCT06653998

This study is testing if getting ICU patients moving and doing rehab exercises early can help them recover better and faster from their illness.

Quick facts

Study typeObservational
Enrollment220 (estimated)
Ages18 Years and up
SexAll
SponsorSanitas University Academic / other
Locations4 sites (Bogotá, Bogota D.C. and 3 other locations)
Trial IDNCT06653998 on ClinicalTrials.gov

What this trial studies

This study assesses the feasibility and safety of implementing early mobilization and rehabilitation strategies for patients in intensive care units (ICUs) who are at risk of developing ICU-acquired weakness. It involves a multicenter prospective cohort approach, where interventions such as passive and active mobilization are initiated within 24-48 hours of ICU admission. The study aims to identify barriers to early mobilization and evaluate the outcomes related to muscle strength and overall recovery. By focusing on a structured process and multidisciplinary approach, the research seeks to improve functional outcomes and reduce the duration of ICU and hospital stays.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who are admitted to intensive care units.

Not a fit: Patients requiring extracorporeal membrane oxygenation (ECMO) or those with severe hemodynamic instability may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly enhance recovery and reduce complications for critically ill patients in ICUs.

How similar studies have performed: Previous studies have shown that early mobilization in ICU settings is feasible and can lead to improved patient outcomes, indicating a promising approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients ≥ 18 years of age admitted to the intensive care units.

Exclusion Criteria:

* Patients requiring extracorporeal membrane oxygenation (ECMO).
* Patients without indication for early mobilisation in the ICU (severe hemodynamic instability, acute brain or spinal injury with rest orders, anaemia (Hb \<8 mg/dl), thrombocytopenia (platelets \<50,000), active systemic inflammatory response according to institutional protocols).
* Patients in the postoperative period of cardiac transplantation.

Where this trial is running

Bogotá, Bogota D.C. and 3 other locations

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Intensive Care Unit Acquired WeaknessIntensive Care Unit PatientsIntensive Care UnitsMuscle WeaknessEarly MobilizationRehabilitation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.