Evaluating diagnostic tests for Primary Ciliary Dyskinesia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of current diagnostic tests for Primary Ciliary Dyskinesia (PCD), focusing on nasal nitric oxide (nNO) testing. Participants referred for PCD diagnosis will have their clinical information collected in a secure database and may undergo nNO testing, which is increasingly recognized for its diagnostic value in appropriate clinical contexts. The study aims to enhance the understanding and utility of these diagnostic methods in clinical care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Referred to center for PCD diagnosis considerations
* Ability to perform study procedures
* Age greater than 2 years of age

Exclusion Criteria:

* Age less than 2 years of age Inability to perform informed consent

Where it's running

• Vanderbilt Children's hospital
  Nashville, Tennessee, United States Recruiting

Study contacts

• Study coordinator: Michael O'Connor, MD
• Email: michael.g.oconnor@vumc.org
• Phone: 615.343.7617

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Bronchial hyperresponsiveness in children with primary ciliary dyskinesia

  This will see if children with primary ciliary dyskinesia have sensitive airways (bronchial hyperresponsiveness) by using a methacholine breathing challenge and related tests.

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• PALMIRE cohort: phenotyping inflammatory lung diseases to enable personalized care

  This project will collect clinical, imaging, and biological data from adults with asthma, COPD, bronchiectasis, cystic fibrosis, primary ciliary dyskinesia, or interstitial lung disease to try to identify disease subtypes and markers that could guide more personalized care.

  Recruiting CHU de Reims · Reims · NCT07274631

• Thermal spa treatment to improve symptoms of primary ciliary dyskinesia

  We will try a 3-week thermal spa treatment in adults with primary ciliary dyskinesia to see if it improves ear, nose, and throat symptoms, lowers infection and antibiotic rates, and helps hearing and lung function.

  Recruiting Association Francaise pour la Recherche Thermale · Nice · NCT07029594

• Glycine and magnesium plus thiamine for primary ciliary dyskinesia

  This trial will test whether daily oral glycine and magnesium with thiamine, alone or combined, can help people aged 5 and older with primary ciliary dyskinesia clear mucus and breathe better.

  Recruiting Instituto Nacional de Enfermedades Respiratorias · Mexico City · NCT06959251

• Observational study on Primary Ciliary Dyskinesia

  This study looks at people with Primary Ciliary Dyskinesia to see what factors might affect how severe their condition is and to help improve their care.

  Recruiting at 18 sites Institut National de la Santé Et de la Recherche Médicale, France · Besançon and 31 other locations · NCT05951478

• Using nasal nitric oxide testing to improve diagnosis of primary ciliary dyskinesia

  This study is testing if a simple nasal test can help doctors diagnose primary ciliary dyskinesia in people aged 2 and older who show symptoms of the condition.

  Recruiting Connecticut Children's Medical Center · Hartford, Connecticut · NCT05889013

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.