Evaluating diagnostic tests for Primary Ciliary Dyskinesia
Utility of PCD Diagnostics to Improve Clinical Care
NA · Vanderbilt University Medical Center · NCT03704207
This study is testing how well nasal nitric oxide testing works for diagnosing Primary Ciliary Dyskinesia in people who are being checked for this condition.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 1 Year and up |
| Sex | All |
| Sponsor | Vanderbilt University Medical Center (other) |
| Locations | 1 site (Nashville, Tennessee) |
| Trial ID | NCT03704207 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of current diagnostic tests for Primary Ciliary Dyskinesia (PCD), focusing on nasal nitric oxide (nNO) testing. Participants referred for PCD diagnosis will have their clinical information collected in a secure database and may undergo nNO testing, which is increasingly recognized for its diagnostic value in appropriate clinical contexts. The study aims to enhance the understanding and utility of these diagnostic methods in clinical care.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals over the age of 2 who have been referred for evaluation of Primary Ciliary Dyskinesia.
Not a fit: Patients under the age of 2 or those unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic accuracy for patients with Primary Ciliary Dyskinesia.
How similar studies have performed: While the utility of nNO testing is gaining recognition, this study aims to further validate its effectiveness, making it a novel approach in this specific context.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Referred to center for PCD diagnosis considerations * Ability to perform study procedures * Age greater than 2 years of age Exclusion Criteria: * Age less than 2 years of age Inability to perform informed consent
Where this trial is running
Nashville, Tennessee
- Vanderbilt Children's hospital — Nashville, Tennessee, United States (RECRUITING)
Study contacts
- Study coordinator: Michael O'Connor, MD
- Email: michael.g.oconnor@vumc.org
- Phone: 615.343.7617
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Primary Ciliary Dyskinesia