Evaluating dexmedetomidine's effect on gastric emptying during laparoscopic cholecystectomy
The Effect of Dexmedetomidine on Gastric Emptying, Assessed by Ultrasound, in Patients Undergoing Laparoscopic Cholecystectomy: A Prospective Randomized Trial.
This study is testing if giving dexmedetomidine during gallbladder surgery can help patients' stomachs empty faster and reduce nausea afterward.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 21 Years to 65 Years |
| Sex | All |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta, El-Gharbia) |
| Trial ID | NCT06634524 on ClinicalTrials.gov |
What this trial studies
This study aims to assess how dexmedetomidine influences gastric emptying in patients undergoing laparoscopic cholecystectomy, using gastric ultrasound for evaluation. Delayed gastrointestinal function and postoperative nausea are common issues following this type of surgery, often exacerbated by anesthetic agents. By utilizing dexmedetomidine, which has been shown to reduce surgical stress and improve gastrointestinal function, the study seeks to provide insights into its potential benefits. Participants will receive either dexmedetomidine or normal saline during their procedure to compare outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 21 to 65, of both sexes, who are classified as ASA physical status I-II and are scheduled for elective laparoscopic cholecystectomy.
Not a fit: Patients with gastrointestinal abnormalities, obesity, or those on certain medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved postoperative recovery and reduced nausea for patients undergoing laparoscopic cholecystectomy.
How similar studies have performed: Previous studies have indicated positive outcomes with dexmedetomidine in enhancing postoperative gastrointestinal function, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 21 to 65 years old. * Both sexes. * American Society of Anesthesiologists (ASA) physical status I-II. * Undergoing elective laparoscopic cholecystectomy surgery Exclusion Criteria: * Patient's refusal. * Patients with abnormalities in gastrointestinal tracts (including previous esophageal or gastric surgery, tumors or stricture). * Failure to follow preoperative fasting guidelines. * Patients with a body mass index ≥ 35 * Patients on regular treatment of antacids or prokinetic. * Presence of history of disease causing an increase in the incidence of delayed gastric emptying such as: diabetes mellitus, obesity or electrolyte disturbances. * Pregnancy. * Presence of hepatic or renal dysfunction. * Presence of existing condition causing bradycardia such as heart block, or patients on regular calcium channel blockers or beta blockers.
Where this trial is running
Tanta, El-Gharbia
- Tanta University — Tanta, El-Gharbia, Egypt (Recruiting)
Study contacts
- Study coordinator: Noran H Borg, MBBCh
- Email: Theblackrosen@gmail.com
- Phone: 00201023502471
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.