Evaluating coronary blood flow and resistance in patients with angina

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the feasibility of using intracoronary adenosine during evaluations of coronary flow reserve (CFR) and index of microcirculatory resistance (IMR) in patients experiencing angina. It will measure the repeatability of CFR and IMR assessments while hyperemia is induced by adenosine and evaluate the correlation between coronary waveform signals and physiological ischemia as defined by fractional flow reserve (FFR) and CFR. Participants will undergo these assessments in a catheterization laboratory, followed by a three-year clinical event follow-up to determine the predictive value of FFR, CFR, and IMR on major adverse cardiovascular outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participants with angina

Exclusion Criteria:

* Severe valvular heart disease
* History of asthma
* Heart rate less than 50 beats per minute
* systolic blood pressure less than 90 mmHg

Where it's running

• National Taiwan University Hospital Hsin-Chu branch
  Hsinchu, Taiwan Recruiting

Study contacts

• Study coordinator: Chien-Boon Jong, MD
• Email: jgboon0407@gmail.com
• Phone: 035322140

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.