Evaluating congestion in patients with acute heart failure at discharge
Acute Heart Failure - COngestion Discharge Evaluation. Évaluation de la Congestion à la Sortie d'Hospitalisation Pour Insuffisance Cardiaque aiguë.
NA · Central Hospital, Nancy, France · NCT04332692
This study is testing new ways to check for fluid buildup in the lungs of patients with acute heart failure when they leave the hospital to see if it can help them recover better.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 110 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Central Hospital, Nancy, France (other) |
| Locations | 1 site (Vandœuvre-lès-Nancy) |
| Trial ID | NCT04332692 on ClinicalTrials.gov |
What this trial studies
This study focuses on patients hospitalized for acute heart failure and aims to improve discharge outcomes by assessing congestion using various methods, including clinical examinations and advanced imaging techniques. The goal is to adapt treatment based on a standardized evaluation of lung congestion, which is currently lacking in clinical practice. By utilizing Doppler ultrasounds and biological assessments, the study seeks to establish a multimodal approach to better manage acute heart failure at discharge.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are hospitalized for acute heart failure and are clinically ready for discharge.
Not a fit: Patients with severe comorbidities, those on dialysis, or individuals with significant pulmonary pathology may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly reduce the risk of death and re-hospitalization for patients with acute heart failure.
How similar studies have performed: While the approach of using multimodal congestion assessment is promising, it is not widely tested, making this study a potentially novel contribution to the field.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients hospitalised for acute heart failure. * Patients considered clinically discharging from hospitalisation for acute heart failure. * Age ≥18 years * Patients having received complete information regarding the study design and having signed their informed consent form. * Patient affiliated to or beneficiary of a social security scheme. Exclusion Criteria: * Comorbidity for which the life expectancy is ≤ 3 months * Dialysis patient (peritoneal dialysis or hemodialysis) or patients with glomerular filtration rate \<15 ml/min/m2 at inclusion. * History of lobectomy or pneumonectomy lung surgery * Severe pulmonary or pleural pathology preventing reliable acquisition of lung ultrasound images: severe emphysema, chronic pleurisy, pulmonary fibrosis, etc. * Pregnant woman, parturient or nursing mother * Adult person subject to a legal protection measure (guardianship, curatorship, safeguard of justice) * Adult person who is unable to give consent * Person deprived of liberty by a judicial or administrative decision, * Person subject to psychiatric care pursuant to Articles L. 3212-1 and L. 3213-1 of the Public Health Code.
Where this trial is running
Vandœuvre-lès-Nancy
- CHRU de Nancy — Vandœuvre-lès-Nancy, France (RECRUITING)
Study contacts
- Principal investigator: Nicolas GIRERD, MD,PhD — CHRU of Nancy
- Study coordinator: Nicolas GIRERD, MD,PhD
- Email: n.girerd@chru-nancy.fr
- Phone: + 33 3 83 15 73 22
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Acute Heart Failure