Evaluating congestion in chronic heart failure patients
Official title: Évaluation de la Congestion en Ambulatoire Chez Les Patients Atteints d'Insuffisance Cardiaque Chronique. CHF-COV (Chronic Heart Failure - COngestion eValuation)
Run by Central Hospital, Nancy, France · NCT05089149 · Data updated 2026-11-12
This study is trying to find out if certain signs of congestion in people with chronic heart failure can help predict their risk of being hospitalized or dying within two years.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Central Hospital, Nancy, France Academic / other |
| Locations | 2 sites (Vandœuvre-lès-Nancy and 1 other locations) |
| Status | Recruiting |
| Started | December 14, 2021 |
| Main results expected | December 14, 2028 |
| Study ends | June 14, 2029 |
| Registry record updated | June 5, 2023 |
| Trial ID | NCT05089149 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older with chronic heart failure admitted for scheduled hospitalization or consultation.
✕Probably not a fit
Patients with severe comorbidities, those on dialysis, or individuals unable to provide consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on chronic heart failure (HF) patients, particularly those experiencing congestion, which is a major cause of hospitalization and symptoms. It aims to identify various congestion markers through clinical examinations, laboratory tests, and ultrasound evaluations during a scheduled consultation or day hospitalization. The study will monitor these markers to assess their association with the risk of all-cause death or hospitalization for acute HF within 24 months. By integrating multiple evaluation methods, the study seeks to enhance the understanding of congestion in HF management.
Why it matters
Potential benefit: If successful, this study could lead to improved monitoring and management strategies for chronic heart failure patients, potentially reducing hospitalizations and mortality.
How similar studies have gone: Other studies have shown success in using multi-modality evaluations for heart failure management, suggesting this approach is promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with chronic acute heart failure admitted in hospital for scheduled day hospitalization or consultation * Age ≥18 years * Patients having received complete information regarding the study design and having signed their informed consent form. * Patient affiliated to or beneficiary of a social security scheme. Exclusion Criteria: * Comorbidity for which the life expectancy is ≤ 3 months * Dialysis patient (peritoneal dialysis or hemodialysis) or patients with glomerular filtration rate \<15 ml/min/m2 at inclusion. * History of lobectomy or pneumonectomy lung surgery * Severe pulmonary or pleural pathology preventing reliable acquisition of lung ultrasound images: severe emphysema, chronic pleurisy, pulmonary fibrosis, etc. * Pregnant woman, parturient or nursing mother * Adult person subject to a legal protection measure (guardianship, curatorship, safeguard of justice) * Adult person who is unable to give consent * Person deprived of liberty by a judicial or administrative decision, * Person subject to psychiatric care pursuant to Articles L. 3212-1 and L. 3213-1 of the Public Health Code.
Where it's running
-
CHRU de Nancy
Vandœuvre-lès-Nancy, France Recruiting -
CHRU de Nancy
Vandœuvre-lès-Nancy, France Not yet recruiting
Similar studies
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This study will test whether adding vericiguat to usual heart‑failure treatment helps adults with stable HFrEF improve right‑ventricular function and heart remodeling over 12 months.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.