Evaluating CO2 levels and blood vessel response in septic shock patients
co2 Gap Changes Versus Inferior Vena Cava Collapsibility in Relation to Cardiac Index as a Prognostic Value in Septic Shock
This study is testing if monitoring CO2 levels can help doctors better understand and treat patients with severe septic shock in the ICU.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06119815 on ClinicalTrials.gov |
What this trial studies
This study investigates the relationship between CO2 gap changes and inferior vena cava collapsibility in patients experiencing septic shock, aiming to assess their prognostic value in relation to cardiac index. By focusing on patients with severe septic shock who have been in the ICU for over 24 hours, the study seeks to identify early indicators of tissue hypoperfusion. The intervention involves monitoring CO2 levels to improve treatment outcomes for septic shock, which has a high mortality rate. The findings could lead to better management strategies for this critical condition.
Who should consider this trial
Good fit: Ideal candidates for this study are adults diagnosed with severe septic shock who have been in the ICU for more than 24 hours.
Not a fit: Patients under 18 years old, those with COPD, heart failure, or active pulmonary edema may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance early detection and treatment of septic shock, potentially reducing mortality rates.
How similar studies have performed: While the specific approach of this study may be novel, previous studies have indicated the importance of early recognition of tissue hypoperfusion in septic shock management.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * o Patients with a diagnosis of severe septic shock. * Patients With an ICU stay of more than 24 hours Exclusion Criteria: * o Age \<18 years old. * Patients with (COPD). * Patients with heart failure. * Patients with active pulmonary edema
Where this trial is running
Sohag
- Sohag University hospitals — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: islam i Ahmed, assisstant lecturer
- Email: islam.mohamed@med.sohag.edu.eg
- Phone: 01090579066
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.