Evaluating causes of preeclampsia in pregnancies using donated oocytes
Immunological and Cardiovascular Phenotyping of Oocyte-donation Pregnancies
This study is trying to find out what causes preeclampsia in pregnancies that use donated eggs by looking at medical histories and samples from moms and babies.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | Female |
| Sponsor | Charite University, Berlin, Germany Academic / other |
| Locations | 1 site (Berlin) |
| Trial ID | NCT04731012 on ClinicalTrials.gov |
What this trial studies
This study aims to investigate the underlying causes of preeclampsia specifically in pregnancies that involve oocyte donation. Researchers will collect detailed medical histories, administer questionnaires, and analyze blood, urine, and placental samples to identify various factors that contribute to the increased risk of preeclampsia in these pregnancies. The observational nature of the study allows for a comprehensive understanding of immunological and cardiovascular changes associated with this condition.
Who should consider this trial
Good fit: Ideal candidates for this study are pregnant individuals who have conceived through oocyte donation.
Not a fit: Patients with severe autoimmune disorders may not benefit from this study due to exclusion criteria.
Why it matters
Potential benefit: If successful, this study could lead to improved management and prevention strategies for preeclampsia in oocyte-donation pregnancies.
How similar studies have performed: While studies on preeclampsia exist, this specific focus on oocyte-donation pregnancies is relatively novel and may provide new insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * pregnancy Exclusion Criteria: * severe auto immune disorders
Where this trial is running
Berlin
- Experimental and Clinical Research Center (ECRC) — Berlin, Germany (Recruiting)
Study contacts
- Study coordinator: Florian Herse, DSc
- Email: florian.herse@charite.de
- Phone: +49 30 450 540 434
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.