Evaluating cardiovascular risks in patients starting dialysis
Official title: Evaluation of Non Traditional Cardiovascular Risk Factors in Chronic Kidney Disease Patients Starting Dialysis
Run by University Hospital, Montpellier · NCT02813642 · Data updated 2026-11-12
This study is testing how certain bone markers in people starting dialysis for kidney disease might affect their heart health over two years.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | University Hospital, Montpellier Academic / other |
| Locations | 5 sites (Castelnau-le-Lez and 4 other locations) |
| Status | Recruiting |
| Started | December 8, 2011 |
| Main results expected | December 2026 |
| Study ends | February 2027 |
| Registry record updated | April 14, 2022 |
| Trial ID | NCT02813642 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with chronic renal failure who are beginning dialysis therapy.
✕Probably not a fit
Patients who are pregnant or those with chronic renal failure not yet on dialysis will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to assess the relationship between levels of bone mineral markers and the progression of vascular calcification in patients who are beginning dialysis treatment for chronic kidney disease. Over a two-year follow-up period, researchers will measure plasma osteoprotegerin and fibroblast growth factor 23 levels, as well as vascular calcification scores. The goal is to better understand how these factors contribute to cardiovascular risks in this patient population.
Why it matters
Potential benefit: If successful, this study could lead to improved management of cardiovascular risks in patients starting dialysis.
How similar studies have gone: Other studies have explored cardiovascular risks in dialysis patients, but this specific approach focusing on bone mineral metabolism markers is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient who has signed the written consent form * Patient with chronic renal failure starting dialysis therapy Exclusion Criteria: * Pregnancy * Patient with chronic renal failure not yet on dialysis therapy
Where it's running
-
Centre Hémodialyse du Lez
Castelnau-le-Lez, France Recruiting -
Aider
Montpellier, France Recruiting -
CHU Montpellier, Nephrology department
Montpellier, France Recruiting -
CH Nimes, Nephrology department
Nîmes, France Recruiting -
CH Perpignan, Nephrology department
Perpignan, France Recruiting
Study contacts
- Principal investigator: Jean-Paul Cristol, Prof — CHU Lapeyronie, Department of Biochemistry and Hormonology, Montpellier, FRANCE
- Study coordinator: Jean-Paul Cristol, Prof
- Email: jp-cristol@chu-montpellier.fr
- Phone: +33(0)4 67 33 83 15
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.