Clinical trial Recruiting at 5 sites Interventional Ages 18 to 90

Evaluating cardiovascular risks in patients starting dialysis

Official title: Evaluation of Non Traditional Cardiovascular Risk Factors in Chronic Kidney Disease Patients Starting Dialysis

Run by University Hospital, Montpellier · NCT02813642 · Data updated 2026-11-12

This study is testing how certain bone markers in people starting dialysis for kidney disease might affect their heart health over two years.

Quick facts

Study typeInterventional
Ages18 Years to 90 Years
SexAll
Enrollment400 (estimated)
SponsorUniversity Hospital, Montpellier
Academic / other
Locations5 sites (Castelnau-le-Lez and 4 other locations)
StatusRecruiting
StartedDecember 8, 2011
Main results expectedDecember 2026
Study endsFebruary 2027
Registry record updatedApril 14, 2022
Trial IDNCT02813642 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with chronic renal failure who are beginning dialysis therapy.

Probably not a fit

Patients who are pregnant or those with chronic renal failure not yet on dialysis will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the relationship between levels of bone mineral markers and the progression of vascular calcification in patients who are beginning dialysis treatment for chronic kidney disease. Over a two-year follow-up period, researchers will measure plasma osteoprotegerin and fibroblast growth factor 23 levels, as well as vascular calcification scores. The goal is to better understand how these factors contribute to cardiovascular risks in this patient population.

Why it matters

Potential benefit: If successful, this study could lead to improved management of cardiovascular risks in patients starting dialysis.

How similar studies have gone: Other studies have explored cardiovascular risks in dialysis patients, but this specific approach focusing on bone mineral metabolism markers is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient who has signed the written consent form
* Patient with chronic renal failure starting dialysis therapy

Exclusion Criteria:

* Pregnancy
* Patient with chronic renal failure not yet on dialysis therapy

Where it's running

  • Centre Hémodialyse du Lez
    Castelnau-le-Lez, France
    Recruiting
  • Aider
    Montpellier, France
    Recruiting
  • CHU Montpellier, Nephrology department
    Montpellier, France
    Recruiting
  • CH Nimes, Nephrology department
    Nîmes, France
    Recruiting
  • CH Perpignan, Nephrology department
    Perpignan, France
    Recruiting

Study contacts

  • Principal investigator: Jean-Paul Cristol, Prof — CHU Lapeyronie, Department of Biochemistry and Hormonology, Montpellier, FRANCE
  • Study coordinator: Jean-Paul Cristol, Prof
  • Email: jp-cristol@chu-montpellier.fr
  • Phone: +33(0)4 67 33 83 15

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.