Evaluating blood flow conditions in the arms of patients with kidney issues
Evaluation of Macro and Microcirculatory Arterial Condition of the Upper Limb in Insufficiently Renal Patients
This study is testing how blood flow works in the arms of patients with kidney problems who might need dialysis to see if it can help identify any issues with their arteries.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Grenoble Academic / other |
| Locations | 1 site (Grenoble Cedex 9) |
| Trial ID | NCT04451018 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the macro and microcirculatory arterial conditions of the upper limbs in patients with renal insufficiency. It focuses on patients who are candidates for dialysis and may exhibit signs of digital ischemia. The methodology includes ultrasound evaluations to characterize arterial conditions and assess the hemodynamics of arteriovenous fistulas. The study seeks to establish formal criteria for diagnosing arterial disease in these patients.
Who should consider this trial
Good fit: Ideal candidates include chronic renal failure patients who are either pre-dialysis or have arteriovenous fistulas with signs of digital ischemia.
Not a fit: Patients who are not experiencing any symptoms of ischemia or those who are not candidates for dialysis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the management of hand ischemia in renal patients, potentially enhancing their quality of life and functional outcomes.
How similar studies have performed: While there is limited data on similar studies, the approach of using ultrasound to evaluate vascular conditions in renal patients is gaining interest, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Chronic renal failure patient with nephrologist's decision to pre-dialysis Or Chronic renal insufficient patient with arteriovenous fistula of the upper limb and sign of digital ischemia (cold hand, digital ulcer, digital necrosis) Agreement on the study's non-opposition form Age above or equal 18 years Patient affiliated with a social security plan Exclusion Criteria: * Subject under guardianship or subject deprived of liberty Failure to obtain patient's consent
Where this trial is running
Grenoble Cedex 9
- Chu Grenoble Alpes — Grenoble Cedex 9, France (Recruiting)
Study contacts
- Principal investigator: Sophie BLAISE — University Hospital, Grenoble
- Study coordinator: Sophie BLAISE
- Email: SBlaise@chu-grenoble.fr
- Phone: +33(0)476 76 55 47
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.