Evaluating biomarkers for diagnosing PCOS in young women
Official title: Polycystic Ovarian Syndrome (PCOS) in Human Adolescent and Young Adult Females - Biomarker Evaluation Study (PHOEBE)
Run by University Hospital Erlangen · NCT06642831 · Data updated 2026-11-12
This study is testing new blood markers to see if they can help doctors better diagnose Polycystic Ovarian Syndrome (PCOS) in young women aged 15-25.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 15 Years to 25 Years |
| Sex | Women only |
| Enrollment | 380 (estimated) |
| Sponsor | University Hospital Erlangen Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Erlangen) |
| Status | Recruiting |
| Started | January 31, 2023 |
| Main results expected | December 2026 |
| Study ends | March 2027 |
| Registry record updated | October 15, 2024 |
| Trial ID | NCT06642831 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are female adolescents and young adults aged 15-25 who may be experiencing symptoms of PCOS.
✕Probably not a fit
Patients who have recently started menstruating, are using hormonal contraceptives, or have major ovarian abnormalities will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to validate biomarkers that can help diagnose Polycystic Ovarian Syndrome (PCOS) in adolescent and young adult women aged 15-25. Participants will attend a single visit for clinical data collection and a blood draw to measure relevant serum parameters. Those diagnosed with PCOS will have two follow-up visits to monitor treatment and collect additional data. The study focuses on improving diagnostic accuracy for PCOS in this age group.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and timely diagnoses of PCOS in young women.
How similar studies have gone: Other studies have shown promise in using biomarkers for diagnosing PCOS, but this specific approach is focused on a younger demographic.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female subjects age 15-25 years * Signed written informed consent Exclusion Criteria: * Less than 1 years from onset of menarche * Use of hormonal contraceptives * Documented ongoing pregnancy * Major ovarian abnormalities, including subject with only one ovary, cysts and solid masses \> 2 cm as detected by transvaginal ultrasound * Malignancy ( documented malignancy, documentation of current radiation therapy or chemotherapy in medical record)
Where it's running
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Department of Obstetrics and Gynecology, University Erlangen Hospital, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen, Germany
Erlangen, Germany Recruiting
Study contacts
- Principal investigator: Ralf Dittrich, Prof. — University Hospital Erlangen
- Study coordinator: Laura Lotz, Dr. med.
- Email: laura.lotz@uk-erlangen.de
- Phone: +49 9131 85 44023
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Can Milamend Hormone Balance help with PCOS symptoms in women
This study will see if Milamend Hormone Balance can help improve hormonal health and quality of life for women with self-reported PCOS symptoms.
-
Diaphragmatic Breathing to Improve Sleep in Women with PCOS
This study tests whether diaphragmatic breathing exercises can improve sleep quality for women with PCOS who have sleep problems.
-
Continuous glucose monitoring in PCOS
This study tests how blood sugar changes over time in adults with PCOS using a continuous glucose monitor.
-
Comparing two methods to predict ovulation outcomes in women with PCOS
This study is testing two different methods to see which one better predicts ovulation success in women with PCOS who are trying to get pregnant.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.