Evaluating biomarkers for coronary heart disease prognosis
Official title: A Prospective Longitudinal Multi-Omics Cohort of Patients With Coronary Heart Disease Undergoing Coronary Angiography
Run by Shandong First Medical University · NCT05699629 · Data updated 2026-11-12
This study is trying to find out which blood and stool markers can help predict health outcomes for people with coronary heart disease over two years.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50000 (estimated) |
| Sponsor | Shandong First Medical University Academic / other |
| Locations | 1 site (Jinan, Shandong) |
| Status | Recruiting |
| Started | January 21, 2022 |
| Main results expected | January 21, 2027 |
| Study ends | January 21, 2027 |
| Registry record updated | February 13, 2023 |
| Trial ID | NCT05699629 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals diagnosed with coronary heart disease or those experiencing unexplained chest pain requiring coronary angiography.
✕Probably not a fit
Patients with malignant tumors, infectious diseases, advanced liver diseases, or those unwilling to provide informed consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to recruit patients diagnosed with coronary heart disease who are undergoing coronary angiography and follow them for at least two years. The study will track the incidence of major adverse cardiovascular events (MACE), including mortality and rehospitalization, while collecting blood and fecal samples for analysis. Additionally, it will gather comprehensive data on patients' socio-demographic factors, lifestyle, and medical history to investigate biomarkers and factors contributing to poor prognosis in coronary heart disease through multi-omics analysis.
Why it matters
Potential benefit: If successful, this study could lead to improved prognostic tools for patients with coronary heart disease, enhancing their management and outcomes.
How similar studies have gone: Other studies have shown success in using multi-omics approaches to evaluate cardiovascular diseases, indicating potential for this study's methodology.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosed as coronary heart disease or with unexplained chest pain needed to undergo coronary angiography. * Healthy subjects undergoing routine physical examination in the physical examination department and willing to sign informed consent will be recruited as control subjects. Exclusion Criteria: * With malignant tumors, infectious diseases and advanced liver diseases. * Won't sign an inform consent.
Where it's running
-
Shandong First Medical University
Jinan, Shandong, China Recruiting
Study contacts
- Study coordinator: Rong Huang, Dr.
- Email: huangrong9277@163.com
- Phone: 18854125717
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.