Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating biomarkers for coronary heart disease prognosis

Official title: A Prospective Longitudinal Multi-Omics Cohort of Patients With Coronary Heart Disease Undergoing Coronary Angiography

Run by Shandong First Medical University · NCT05699629 · Data updated 2026-11-12

This study is trying to find out which blood and stool markers can help predict health outcomes for people with coronary heart disease over two years.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment50000 (estimated)
SponsorShandong First Medical University
Academic / other
Locations1 site (Jinan, Shandong)
StatusRecruiting
StartedJanuary 21, 2022
Main results expectedJanuary 21, 2027
Study endsJanuary 21, 2027
Registry record updatedFebruary 13, 2023
Trial IDNCT05699629 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals diagnosed with coronary heart disease or those experiencing unexplained chest pain requiring coronary angiography.

Probably not a fit

Patients with malignant tumors, infectious diseases, advanced liver diseases, or those unwilling to provide informed consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to recruit patients diagnosed with coronary heart disease who are undergoing coronary angiography and follow them for at least two years. The study will track the incidence of major adverse cardiovascular events (MACE), including mortality and rehospitalization, while collecting blood and fecal samples for analysis. Additionally, it will gather comprehensive data on patients' socio-demographic factors, lifestyle, and medical history to investigate biomarkers and factors contributing to poor prognosis in coronary heart disease through multi-omics analysis.

Why it matters

Potential benefit: If successful, this study could lead to improved prognostic tools for patients with coronary heart disease, enhancing their management and outcomes.

How similar studies have gone: Other studies have shown success in using multi-omics approaches to evaluate cardiovascular diseases, indicating potential for this study's methodology.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed as coronary heart disease or with unexplained chest pain needed to undergo coronary angiography.
* Healthy subjects undergoing routine physical examination in the physical examination department and willing to sign informed consent will be recruited as control subjects.

Exclusion Criteria:

* With malignant tumors, infectious diseases and advanced liver diseases.
* Won't sign an inform consent.

Where it's running

  • Shandong First Medical University
    Jinan, Shandong, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.