Evaluating Annexin A2 on Monocytes in Antiphospholipid Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the expression of Annexin A2 on the surface of monocytes in patients with primary antiphospholipid syndrome (APS) using flow cytometry. Annexin A2 is a significant protein involved in the regulation of fibrinolysis and has been identified as a new autoantigen in APS. By analyzing the cell membrane expression of this protein, the study seeks to understand its role in the pathogenesis of APS and the associated mechanisms that contribute to the disease. Blood samples will be collected from eligible APS patients to conduct these evaluations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* APS patients who fulfilled the revised criteria for APS

Exclusion Criteria:

* Patients less than 18 years old
* Solid and hematological malignancies
* Other autoimmune diseases
* Cirrhosis

Where it's running

• CHU Amiens
  Amiens, France Recruiting

Study contacts

• Study coordinator: Valéry Salle, MD
• Email: salle.valery@chu-amiens.fr
• Phone: 03 22 66 82 30

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.