Evaluating a screening program for pre-eclampsia in early pregnancy
Far Eastern Memorial Hospital
This study is testing a new screening program for pregnant women to see if it can better identify those at high risk for developing pre-eclampsia early on.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 20 Years and up |
| Sex | Female |
| Sponsor | Far Eastern Memorial Hospital Academic / other |
| Locations | 1 site (Banqiao, New Taipei) |
| Trial ID | NCT04021680 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the clinical effectiveness of a first-trimester screening program designed to identify women at high risk for developing pre-eclampsia. The program combines traditional demographic and medical history assessments with advanced biomarkers, such as uterine artery pulsatility index and pregnancy-associated plasma protein-A, to improve detection rates. Conducted at Far Eastern Memorial Hospital in Taiwan, the study focuses on women aged 20 and older who are between 11 to 13 weeks pregnant. The goal is to evaluate whether this enhanced screening approach can lead to better prevention of pre-eclampsia and its associated complications.
Who should consider this trial
Good fit: Ideal candidates for this study are women aged 20 and older with a singleton pregnancy between 11 to 13 weeks who receive their first-trimester pre-eclampsia screening at the institution.
Not a fit: Patients who are not receiving prenatal care at the institution or who have undergone screening at another facility may not benefit from this study.
Why it matters
Potential benefit: If successful, this screening program could significantly reduce the incidence of pre-eclampsia and improve maternal and perinatal outcomes.
How similar studies have performed: Previous studies have shown that combining maternal factors with biomarkers can improve detection rates for pre-eclampsia, indicating a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: - Women who are 20 years of age or older with singleton pregnancy between 11 to 13 + 6 weeks and received first trimester pre-eclampsia screening test in this institution. Exclusion Criteria: * Women who are not regularly inspected or not receiving prenatal care in this institution. * Women who received first trimester pre-eclampsia screening test at other institution
Where this trial is running
Banqiao, New Taipei
- Department of Obstetrics and Gynecology, Far-Eastern Memorial Hospital — Banqiao, New Taipei, Taiwan (Recruiting)
Study contacts
- Study coordinator: Sheng-Mou Hsiao, MD
- Email: smhsiao2@gmail.com
- Phone: +88689667000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.