Clinical trial Recruiting at 1 site Early Phase 1 Interventional Ages 18 and up

Evaluating a new radiotracer for cancer imaging

Official title: 68Ga-JH04 PET/CT: Dosimetry and Biodistribution Study in Patients With Various Cancers

Run by First Affiliated Hospital of Fujian Medical University · NCT06438250 · Data updated 2026-11-12

This study is testing a new imaging agent for cancer that helps doctors see tumors better by focusing on a specific protein found in cancer cells.

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Ages18 Years and up
SexAll
Enrollment5 (estimated)
SponsorFirst Affiliated Hospital of Fujian Medical University
Academic / other
Drugs / interventionsradiation
Locations1 site (Fuzhou, Fujian)
StatusRecruiting
StartedMarch 1, 2024
Main results expectedMay 1, 2025
Study endsDecember 31, 2025
Registry record updatedNovember 14, 2024
Trial IDNCT06438250 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients with various solid tumors who have confirmed histopathological findings.

Probably not a fit

Patients who are pregnant, lactating, or have severe hepatic and renal insufficiency may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the safety, biodistribution, and radiation dosimetry of a novel radiotracer called 68Ga-JH04, which targets fibroblast activation protein (FAP) in patients with various types of cancer. The research focuses on understanding how well this radiotracer accumulates in tumors compared to normal tissues, leveraging the overexpression of FAP in malignant neoplasms. By assessing the dosimetric characteristics of 68Ga-JH04, the study aims to provide insights into its potential utility for cancer diagnosis and treatment monitoring.

Why it matters

Potential benefit: If successful, this study could enhance the accuracy of cancer imaging and improve treatment planning for patients with malignant tumors.

How similar studies have gone: Previous studies with other FAP-targeting tracers have shown promising results, indicating a potential for success with this novel approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Various solid tumors with available histopathological findings
* Signed informed consent

Exclusion Criteria:

* pregnant or lactational women
* who suffered from severe hepatic and renal insufficiency

Where it's running

  • Department of Nuclear Medicine, First Affiliated Hospital of Fujian Medical University
    Fuzhou, Fujian, China
    Recruiting

Study contacts

  • Principal investigator: Weibing Miao, MD — The First Affiliated Hospital, Fujian Medical University
  • Study coordinator: Weibing Miao, MD
  • Email: miaoweibing@126.com
  • Phone: +86-0591-87981618

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.