Evaluating a new method to measure tumor sugar consumption using PET imaging

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess a novel approach for quantifying glucose consumption in tumors using PET/CT imaging. Participants will undergo a standard FDG PET/CT scan along with a dynamic PET/CT scan to evaluate the effectiveness of the fractional uptake rate (FUR) compared to the traditional standardized uptake value (SUV). Blood samples will be collected at three time points during the examination to support the analysis. The goal is to determine if the FUR provides a more accurate assessment of tumor metabolism than the SUV, which has known limitations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients who receive an 18F FDG PET/CT scan as part of standard care
* Be competent and be 18 years of age or older

Exclusion Criteria:

* Diabetes (fasted blood glucose \> 7 mmol/L)
* Not fasted \> 4 hours
* Physical exercise within 24 hours
* Earlier treatment for carcinoma with radio/chemo-therapy
* Active inflammation (fever \> 38 degrees, CRP \> 5)
* Any condition or medical indication (such as claustrophobia) that indicates that the patient will not be able to lie still for the duration of the dynamic PET/CT examination
* Pregnant or breast feeding

Where it's running

• Academisch ziekenhuis Maastricht
  Maastricht, Limburg, Netherlands Recruiting

Study contacts

• Principal investigator: Roel Wierts, PhD — Medical physicist
• Study coordinator: Sam Springer, MSc
• Email: sam.springer@mumc.nl
• Phone: +31433874907

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.