Clinical trial Recruiting at 1 site Observational Ages 16 to 80

Evaluating 68Ga-FAPI PET/CT for Thyroid Cancer with Lymph Node Metastases

Official title: The Value of 68Ga-FAPI PET/CT in Preoperative Evaluation of Thyroid Cancer with Lymph Node Metastases

Run by Ruijin Hospital · NCT06730529 · Data updated 2026-11-12

This study is testing a new type of imaging called 68Ga-FAPI PET/CT to see if it helps doctors better assess thyroid cancer in patients with lymph node spread before surgery.

Quick facts

Study typeObservational
Ages16 Years to 80 Years
SexAll
Enrollment40 (estimated)
SponsorRuijin Hospital
Academic / other
Locations1 site (Shanghai, Shanghai Municipality)
StatusRecruiting
StartedNovember 29, 2024
Main results expectedDecember 31, 2029
Study endsDecember 31, 2029
Registry record updatedDecember 12, 2024
Trial IDNCT06730529 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 16-80 with a clinical and pathological diagnosis of thyroid cancer that has spread to lymph nodes.

Probably not a fit

Patients with serious comorbidities or those who are pregnant or breastfeeding may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of 68Ga-FAPI PET/CT imaging in the preoperative assessment of thyroid cancer patients with lymph node metastases. Participants will be numbered and have their basic demographic and medical history recorded. Each participant will undergo a 68Ga-FAPI PET/CT scan prior to surgery, and the imaging results will be compared against histopathological findings to determine accuracy and value. The goal is to enhance preoperative evaluation methods for better surgical outcomes.

Why it matters

Potential benefit: If successful, this study could improve the accuracy of preoperative evaluations for thyroid cancer, leading to better treatment planning and outcomes.

How similar studies have gone: While the use of PET/CT imaging in cancer evaluation is established, the specific application of 68Ga-FAPI in thyroid cancer is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Pathological and clinical diagnosis of thyroid cancer with lymph node metastases.
2. Signed and dated informed consent form.
3. Commitment to comply with research procedures and co-operation in the implementation of the full research process.
4. Aged 16-80 years old.

Exclusion Criteria:

1. Patients with serious illnesses that researchers consider unsuitable for participation in this clinical study. Such as severe heart and lung failure, severe bone marrow suppression, severe liver and kidney dysfunction, etc.
2. Intestinal perforation, complete intestinal obstruction.
3. Pregnant women and women who may be pregnant, women who are breastfeeding.
4. Non-compliant person.

Where it's running

  • Ruijin Hospital affiliated to Shanghai Jiao Tong University of Medicine
    Shanghai, Shanghai Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.