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EURO-STIM: Long-term tracking of Inspire therapy for obstructive sleep apnea

Longitudinal Outcomes and Adherence of the Inspire System, EURO-STIM Registry

Observational Inspire Medical Systems, Inc. · NCT06971796

This registry will track people with obstructive sleep apnea who have an Inspire implant to see how they use the device over time and how well they stick with therapy.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
Ages18 Years and up
SexAll
SponsorInspire Medical Systems, Inc. Industry-sponsored
Locations21 sites (Klagenfurt and 20 other locations)
Trial IDNCT06971796 on ClinicalTrials.gov

What this trial studies

EURO-STIM is a longitudinal observational registry collecting real-world outcomes and device adherence data from patients treated with the Inspire upper airway stimulation system. Participants receive routine clinical care with no required study-specific interventions or extra testing, and data are captured during standard follow-up visits. The registry aims to document the life cycle of Inspire use, including therapy adherence, clinical outcomes, and device-related events across multiple European centers. Eligibility is limited to patients implanted with or receiving an Inspire device who can give informed consent and attend routine clinic visits.

Who should consider this trial

Good fit: Adults implanted with or scheduled to receive an Inspire upper airway stimulation device who can give informed consent and will attend routine clinic follow-up are ideal candidates.

Not a fit: People without an Inspire implant, those unlikely to survive a year, or patients unable to attend routine follow-up visits are unlikely to receive benefit from participating.

Why it matters

Potential benefit: If successful, the registry could improve understanding of long-term adherence and outcomes with Inspire, helping clinicians optimize patient selection and management.

How similar studies have performed: Prior controlled trials and registries of hypoglossal nerve stimulation, including earlier Inspire studies, have shown reductions in OSA severity and improved adherence, so this registry extends existing real-world evidence.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

Any patient implanted with or receiving an Inspire implant, who meets the following criteria, is eligible to participate in the registry:

1. Capable of giving informed consent, as required per institution
2. Willing to return for routine clinic visits as required for Inspire therapy management

Exclusion Criteria:

Any patient who meets any of the following criteria will not be eligible to participate in the registry:

1. Has a life expectancy of less than one year
2. Any reason the clinician deems patient is unfit for participation in the study

Where this trial is running

Klagenfurt and 20 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov → Find more trials like this →
Conditions Obstructive Sleep ApneaSleep ApneaOSAInspire
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.