Estimating dental age in children with cleft lip and palate

Evaluation of Dental Age of Children With Cleft Lip and Palate Using Willems Method, Cameriere European Formula, and London Atlas

Observational Istanbul University · NCT05573295

This study is trying to see if children with cleft lip and palate have different dental ages compared to healthy kids by using three different methods to check their teeth development.

Quick facts

Study typeObservational
Enrollment240 (estimated)
Ages5 Years to 14 Years
SexAll
SponsorIstanbul University Academic / other
Locations1 site (Istanbul)
Trial IDNCT05573295 on ClinicalTrials.gov

What this trial studies

This study investigates the differences in dental age between children with cleft lip and palate (CLP) and healthy controls using three methods: the Willems method, the Cameriere European formula, and the London Atlas. It aims to determine if a significant difference exists in dental age, which could lead to the development of a new formula for age estimation in this population. The study involves evaluating tooth eruption and the development of teeth through radiographic analysis. Accurate dental age estimation is crucial for treatment planning and can also aid in forensic assessments.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 5-14 years, both healthy and those with cleft lip and palate, who have no missing left mandibular permanent teeth.

Not a fit: Patients younger than 5 or older than 14 years, those with poor quality radiographs, or those who have received orthodontic or restorative treatments may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve dental treatment planning for children with cleft lip and palate by providing more accurate age estimations.

How similar studies have performed: Other studies have successfully utilized similar methods for dental age estimation, indicating that this approach is well-established.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 5-14 years old
* Healthy children
* Children with CLP
* Patients without missing left mandibular permanent teeth on panoramic radiography

Exclusion Criteria:

* Children younger than 5 years old and older than 14 years (children that cannot be assessed by the Willems and Cameriere method)
* Poor quality panoramic radiography
* Patients who have received orthodontic treatment
* Patients who received restorative or endodontic treatment

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Dental Age EstimationCleft Lip and Palatechildrendental age estimationchronological ageLondon AtlasCameriere European FormulaWillems method
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.