Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Erector spinae versus quadro-iliac nerve blocks for pain after lumbar instrumentation

Official title: Comparison of Ultrasound-Guided Erector Spinae Plane Block and Quadro-Iliac Plane Block for Postoperative Analgesia Management Following Lumbar Instrumentation Surgery

Run by Bursa City Hospital · NCT07354581 · Data updated 2026-11-12

This study will test whether an erector spinae plane block or a quadro-iliac plane block gives better pain relief after elective lumbar instrumentation surgery in adults.

More Pain, Postoperative trials

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment80 (estimated)
SponsorBursa City Hospital
Government
Locations1 site (Bursa)
StatusRecruiting
StartedJanuary 20, 2026
Main results expectedMarch 31, 2026
Study endsJuly 1, 2026
Registry record updatedMarch 31, 2026
Trial IDNCT07354581 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–65 with ASA physical status I–III who are scheduled for elective lumbar instrumentation under general anesthesia and can give informed consent.

Probably not a fit

Patients with exclusion criteria such as anticoagulant use or bleeding diathesis, infection at the block site, allergy to local anesthetics, pregnancy or lactation, prior lumbar spine surgery, diabetes, or significant renal/hepatic impairment are unlikely to be eligible or to receive benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults undergoing elective lumbar instrumentation under general anesthesia will receive one of two ultrasound-guided regional blocks—erector spinae plane block (ESPB) or quadro-iliac plane block (QIPB)—as part of a standardized multimodal analgesia protocol. Postoperative pain scores, opioid consumption, and recovery measures will be recorded to compare analgesic effectiveness between groups. Both blocks are performed under ultrasound guidance with local anesthetic deposited in the relevant fascial plane; ESPB is an established technique while QIPB is a newer approach targeting the plane near the iliac crest. The trial aims to clarify which block provides superior postoperative analgesia and inform perioperative pain management for lumbar spine surgery.

Why it matters

Potential benefit: If successful, the better-performing block could reduce postoperative pain and opioid use, speeding recovery and improving comfort after lumbar instrumentation.

How similar studies have gone: Erector spinae plane block has demonstrated postoperative analgesic benefits in various spinal procedures, while the quadro-iliac plane block is a newer technique with limited comparative clinical data.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 18 and 65 years
* Classified as American Society of Anesthesiologists physical status I-III
* Scheduled for elective lumbar instrumentation surgery under general anesthesia
* Provision of written informed consent

Exclusion Criteria:

* Use of anticoagulant medications or presence of bleeding diathesis
* Known allergy or hypersensitivity to local anesthetics or opioid drugs
* Infection at the planned block site
* Alcohol or drug dependence
* Cognitive impairment preventing reliable pain assessment
* Pregnancy or lactation
* History of previous lumbar spine surgery
* Diabetes mellitus
* Renal or hepatic insufficiency

Where it's running

  • Bursa City Hospital
    Bursa, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.