Erector spinae versus quadro-iliac nerve blocks for pain after lumbar instrumentation
Official title: Comparison of Ultrasound-Guided Erector Spinae Plane Block and Quadro-Iliac Plane Block for Postoperative Analgesia Management Following Lumbar Instrumentation Surgery
Run by Bursa City Hospital · NCT07354581 · Data updated 2026-11-12
This study will test whether an erector spinae plane block or a quadro-iliac plane block gives better pain relief after elective lumbar instrumentation surgery in adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Bursa City Hospital Government |
| Locations | 1 site (Bursa) |
| Status | Recruiting |
| Started | January 20, 2026 |
| Main results expected | March 31, 2026 |
| Study ends | July 1, 2026 |
| Registry record updated | March 31, 2026 |
| Trial ID | NCT07354581 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–65 with ASA physical status I–III who are scheduled for elective lumbar instrumentation under general anesthesia and can give informed consent.
✕Probably not a fit
Patients with exclusion criteria such as anticoagulant use or bleeding diathesis, infection at the block site, allergy to local anesthetics, pregnancy or lactation, prior lumbar spine surgery, diabetes, or significant renal/hepatic impairment are unlikely to be eligible or to receive benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults undergoing elective lumbar instrumentation under general anesthesia will receive one of two ultrasound-guided regional blocks—erector spinae plane block (ESPB) or quadro-iliac plane block (QIPB)—as part of a standardized multimodal analgesia protocol. Postoperative pain scores, opioid consumption, and recovery measures will be recorded to compare analgesic effectiveness between groups. Both blocks are performed under ultrasound guidance with local anesthetic deposited in the relevant fascial plane; ESPB is an established technique while QIPB is a newer approach targeting the plane near the iliac crest. The trial aims to clarify which block provides superior postoperative analgesia and inform perioperative pain management for lumbar spine surgery.
Why it matters
Potential benefit: If successful, the better-performing block could reduce postoperative pain and opioid use, speeding recovery and improving comfort after lumbar instrumentation.
How similar studies have gone: Erector spinae plane block has demonstrated postoperative analgesic benefits in various spinal procedures, while the quadro-iliac plane block is a newer technique with limited comparative clinical data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 18 and 65 years * Classified as American Society of Anesthesiologists physical status I-III * Scheduled for elective lumbar instrumentation surgery under general anesthesia * Provision of written informed consent Exclusion Criteria: * Use of anticoagulant medications or presence of bleeding diathesis * Known allergy or hypersensitivity to local anesthetics or opioid drugs * Infection at the planned block site * Alcohol or drug dependence * Cognitive impairment preventing reliable pain assessment * Pregnancy or lactation * History of previous lumbar spine surgery * Diabetes mellitus * Renal or hepatic insufficiency
Where it's running
-
Bursa City Hospital
Bursa, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Merih Yildiz Eglen, MD
- Email: meriheg@yahoo.com
- Phone: +905059340629
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.