Erector spinae plane blockade for pain relief in children with scoliosis surgery
Pediatric Scoliosis Surgery: Enhanced Recovery With Erector Spinae Plane Blockade Utilizing Surgically Placed Catheters
This study is testing if a special pain relief method can help children feel less pain after spinal surgery for scoliosis while using fewer opioids.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | N/A to 18 Years |
| Sex | All |
| Sponsor | Stanford University Academic / other |
| Locations | 1 site (Palo Alto, California) |
| Trial ID | NCT04153994 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the use of erector spinae plane blockade (ESPB) to provide effective pain relief for pediatric patients undergoing spinal fusion surgery for idiopathic scoliosis. The study aims to evaluate the effectiveness of ESPB as part of a multimodal analgesic approach, potentially reducing reliance on opioids, which have known adverse effects. By injecting local anesthetic into the erector spinae muscle area, the trial seeks to assess the impact on postoperative pain management and inflammatory response. The study includes children classified as ASA I-III who are undergoing a specific surgical procedure.
Who should consider this trial
Good fit: Ideal candidates are children diagnosed with idiopathic scoliosis who are undergoing single-stage posterior spinal instrumentation and fusion.
Not a fit: Patients with congenital or neuromuscular scoliosis, those requiring PICU admission, or those with significant pre-existing pain complaints may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve pain management in pediatric scoliosis surgery patients while minimizing opioid use.
How similar studies have performed: Previous studies have shown promising results with similar regional anesthesia techniques in adult populations, but this specific application in pediatric scoliosis surgery is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA I-III * Diagnosed with Idiopathic scoliosis * Undergoing single-stage posterior spinal instrumentation and fusion Exclusion Criteria: * Thorascopic tethering procedure * Two-stage procedure * Abnormal developmental profile * Congenital/neuromuscular scoliosis * Requiring PICU admission * Known allergy to lidocaine * Known cardiac, renal or liver disease or dysfunction * Pre-existing pain complaints, i.e. on regular analgesic medications * Current psychiatric diagnosis, e.g. anxiety, depression, eating disorder, defined according to DSM criteria. * Requiring non-standard post-op pain management * Any history of seizures * Unplanned staged procedure * Weight \< 5th centile or \> 85th centile for age * Porphyria
Where this trial is running
Palo Alto, California
- Lucille Packard Children's Hospital — Palo Alto, California, United States (Recruiting)
Study contacts
- Study coordinator: Ban Tsui, MD
- Email: bantsui@stanford.edu
- Phone: (650)200-9107
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.