Erector spinae plane block versus transcutaneous radiofrequency for postherpetic neuralgia

Which Is More Effective in the Treatment of Postherpetic Neuralgia: Erector Spinae Plane Block or Transcutaneous Radiofrequency?

Observational Diskapi Teaching and Research Hospital · NCT07400640

This project will see if erector spinae plane block or transcutaneous radiofrequency works better to reduce pain in adults with postherpetic neuralgia.

Quick facts

Study typeObservational
Enrollment50 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorDiskapi Teaching and Research Hospital Academic / other
Locations1 site (Ankara)
Trial IDNCT07400640 on ClinicalTrials.gov

What this trial studies

This is a retrospective observational comparison of two commonly used treatments for postherpetic neuralgia performed at a single algology clinic. Patients who previously received either ultrasound-guided erector spinae plane (ESP) block or transcutaneous radiofrequency (RF) as part of routine care are grouped by the treatment they received. Pain intensity and neuropathic pain features will be compared using Visual Analog Scale (VAS) and S-LANSS scores recorded before treatment, immediately after treatment, and at one-month follow-up. No randomization or changes to clinical care were made for the purposes of this analysis.

Who should consider this trial

Good fit: Adults aged 18–80 with postherpetic neuralgia in the cervical, thoracic, or lumbar regions who had persistent pain despite conservative treatment and a baseline VAS score greater than 5 are the ideal candidates represented in this analysis.

Not a fit: Patients with ophthalmic or extremity postherpetic neuralgia, those who were pregnant, had coagulopathy or antiplatelet therapy, allergy to local anesthetics, or cognitive impairment preventing consent would not be represented and may not benefit from these results.

Why it matters

Potential benefit: If successful, the findings could help clinicians choose the treatment more likely to give better short-term pain relief and reduce neuropathic symptoms for patients with postherpetic neuralgia.

How similar studies have performed: Previous case series and small trials report pain relief with both ESP block and transcutaneous RF for neuropathic pain, but direct head-to-head comparative data are limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Diagnosis of postherpetic neuralgia involving cervical, thoracic, or lumbar regions

Age between 18 and 80 years

Persistent pain despite conservative treatment

Baseline VAS score \> 5

Exclusion Criteria:

Ophthalmic or extremity postherpetic neuralgia

Allergy to local anesthetics

Pregnancy

Coagulopathy or use of antiplatelet therapy

Cognitive impairment preventing informed consent

Where this trial is running

Ankara

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postherpetic NeuralgiaNeuropathic PainHerpes Zosterpostherpetic neuralgia, esp block, transcutaneous rf
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.