Erector spinae plane block versus intrathecal morphine for recovery after cesarean

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective interventional study compares postoperative ESP block with intrathecal morphine for analgesia after elective cesarean section in adult women. Participants who meet inclusion criteria will be assigned to receive either a postoperative ESP block or intrathecal morphine as part of a multimodal analgesic protocol. The primary outcome is quality of recovery measured by the validated QoR-11 questionnaire, with secondary outcomes including pain scores, opioid consumption, opioid-related side effects, time to mobilization, breastfeeding outcomes, and length of hospital stay. Safety exclusions include coagulation disorders, infection at the puncture site, contraindications to neuraxial analgesia, chronic opioid use, and other standard perioperative contraindications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult women aged 18-45 years
* ASA physical status II-III
* Full-term singleton pregnancy scheduled for elective cesarean section under spinal anesthesia

Exclusion Criteria:

* ASA ≥ IV
* Coagulation disorders
* Emergency surgery
* Preoperative infection (including infection at the ESPB puncture site)
* Any contraindication to neuraxial analgesia
* History of chronic pain
* Use of opioids
* Allergy to local anesthetics
* Hypersensitivity to any drug used in the study
* Inability to understand or use verbal pain assessment scales
* Refusal to participate in the study

Where it's running

• AUSL Romagna - Ospedale M.Bufalini
  Cesena, Forlì, Italy Recruiting

Study contacts

• Principal investigator: Domenico P Santonastaso, MD — AUSL Romagna - M. Bufalini Hospital
• Study coordinator: Domenico P Santonastaso, MD
• Email: domenicopietro.santonastaso@auslromagna.it
• Phone: +393492585491

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.