Erector spinae block to lower opioid use after total abdominal hysterectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Total abdominal hysterectomy causes substantial postoperative pain and often requires high perioperative opioid doses, which can slow recovery due to nausea, vomiting, constipation, and respiratory depression. In this interventional Phase 4 protocol, participants undergoing elective total abdominal hysterectomy receive either an erector spinae plane (ESP) block with bupivacaine or a placebo block in the perioperative period. Opioid consumption after surgery, along with common opioid-related side effects and recovery measures, will be recorded and compared between groups. Eligible patients are adults classified as ASA I–III having elective procedures at the study hospital.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* American Society of Anesthesiologists (ASA) class: I, II and III .
* Elective Hysterectomy under General Anesthesia.

Exclusion Criteria:

* Lack of consent
* Body mass index \>35 kg/m2
* Allergic to study medicine
* Opioid abuse or misuse disorder
* Chronic pain

Where it's running

• Kulsoom Internation Hospital
  Islamabad, Federal, Pakistan Recruiting

Study contacts

• Study coordinator: Waqas Anjum, Principal Investigator, MBBS, FCPS
• Email: waqasanjum435@gmail.com
• Phone: +92-310-3308158

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Dexmedetomidine as add-on for refractory cancer pain in palliative care

  This study tests whether adding dexmedetomidine helps improve pain control for adults with cancer in palliative care whose pain remains high despite opioids.

  Recruiting St. Olavs Hospital · Drammen and 3 other locations · NCT07885475

• Opioid-Free Anesthesia in FESS with ERAS

  This study tries a opioid-free anesthesia approach during functional endoscopic sinus surgery to see if pain, nausea, and recovery are improved for adults undergoing this procedure.

  Recruiting Ankara City Hospital Bilkent · Ankara, ÇANKAYA · NCT07812389

• How MOR Activation Affects Stress and Social Behavior, and How Childhood Unpredictability Modulates This in Men and Women

  This study tests whether activating the mu opioid receptor with morphine changes stress responses and social behavior, and whether sex and early life unpredictability alter those effects.

  Recruiting Psychiatric University Hospital, Zurich · Zurich · NCT07778511

• Erector Spinae Plane Block vs Modified Thoracoabdominal Nerve Block After Laparoscopic Cholecystectomy

  Two regional anesthesia techniques are being tested to see which provides better pain control after gallbladder removal surgery.

  Recruiting Alexandria University · Alexandria · NCT07624058

• Pre-surgery preparation program for older adults having lumbar fusion

  This trial will try a 6-week multimodal prehabilitation program to help people aged 75 and older having elective lumbar fusion recover independence and reduce complications after surgery.

  Recruiting at 4 sites Xuanwu Hospital, Beijing · Beijing, Beijing Municipality and 3 other locations · NCT07396077

• Opioid-free versus usual discharge pain plans after major orthopedic surgery.

  This pilot trial will test whether sending adults home after major orthopedic surgery with an opioid-free pain prescription provides pain control similar to the usual opioid-containing prescription.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT07265557

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.