Environments that help reduce NCD risk during pregnancy in Ethiopia
Official title: Enhancing Non-Communicable Disease Prevention Among Pregnant Women Through Healthy Lifestyle Promotion in Four Urban Sites in Ethiopia: A Cluster Randomized Controlled Trial in Primary Health Care Facilities
Run by Norwegian Institute of Public Health · NCT07442318 · Data updated 2026-11-12
This trial tests whether adding structured counseling on healthy eating, activity, and air-pollution reduction to routine antenatal care helps pregnant women in four Ethiopian cities reduce NCD risks.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 1268 (estimated) |
| Sponsor | Norwegian Institute of Public Health Government |
| Locations | 4 sites (Addis Ababa, Addis Ababa and 3 other locations) |
| Status | Recruiting |
| Started | May 11, 2026 |
| Main results expected | April 10, 2027 |
| Study ends | May 2027 |
| Registry record updated | May 28, 2026 |
| Trial ID | NCT07442318 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Pregnant women aged 18 or older, ≤20 weeks gestation, residing in Addis Ababa, Adama, Harar, or Jimma, attending their first ANC visit at participating facilities, and able to provide informed consent.
✕Probably not a fit
Women who have high-risk conditions requiring specialized care or who do not engage with the counseling may not experience the intended benefits.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The ENABLE study is a cluster-randomized trial in 77 urban public health centers across Addis Ababa, Adama, Harar, and Jimma. It compares standard antenatal care with an integrated intervention that includes tailored counseling on diet, physical activity, and air pollution exposure, supported by a digital ANC eRegistry. Health center staff and Urban Health Extension Professionals receive training to deliver the counseling within routine ANC visits, aiming to improve birth outcomes such as birth weight. The study uses a Hybrid Type II design to assess both effectiveness and implementation under real-world primary health care conditions, enrolling about 1,268 pregnant women at ≤20 weeks gestation and following them through delivery.
Why it matters
Potential benefit: If successful, the intervention could reduce NCD risk factors during pregnancy and improve birth outcomes for mothers and newborns.
How similar studies have gone: Similar approaches integrating ANC-based behavioral counseling with digital support have shown promise in improving maternal health behaviors in other settings, though this trial tests effectiveness in Ethiopian primary care.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pregnant women aged 18 years or older * Gestational age ≤20 weeks at the time of enrollment * Residing in one of the four study cities (Addis Ababa, Adama, Harar, or Jimma) * Attending their first antenatal care visit at one of the participating public health facilities * Willing and able to provide informed consent Exclusion Criteria: * Pregnant women identified as high risk at enrollment, including those with pre-existing medical conditions, or other conditions requiring specialized care and who cannot continue receiving standard routine ANC.
Where it's running
-
Addis Ababa
Addis Ababa, Addis Ababa, Ethiopia Recruiting -
Harar
Harar, Harare, Ethiopia Recruiting -
Adama
Adama, Oromiya, Ethiopia Recruiting -
Jimma
Jimma, Oromiya, Ethiopia Recruiting
Study contacts
- Principal investigator: Masresha Tessema, PhD — Ethiopian Public Health Institute
- Study coordinator: Masresha Tessema, PhD
- Email: dr.masresha.tessema@gmail.com
- Phone: +251919782082
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Health for Hungary: Long-term blood and health data collection to study aging and disease onset
This study tests whether routine blood tests plus advanced molecular analyses can help detect the early stages of non-communicable diseases in adults over 40.
-
Examining health inequalities, their patterns, and causes in Thessaly
This project will see if differences in social conditions, physical activity, and access to care explain health gaps among adults in Thessaly, including people with chronic diseases, those treated for opioid use, and incarcerated individuals.
-
Using artificial intelligence to improve breast cancer screening in Norway
This study is testing if using artificial intelligence to help read mammograms can find breast cancer just as well as the usual method done by radiologists.
-
A course to improve wellbeing and mental health
This study tests a course designed to help people with chronic diseases in Norway improve their wellbeing and mental health.
-
Digital interventions for stress management in breast cancer patients
This study is testing two online programs to help breast cancer patients manage stress and see if they can improve their quality of life compared to a control group.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.