Environmental exposures, including cannabis, and lung cancer
Official title: Environment and Lung Cancer
Run by Centre Chirurgical Marie Lannelongue · NCT05119244 · Data updated 2026-11-12
Adults with primary lung cancer aged 18–59 will give blood and hair samples so researchers can try to link cannabis use and other environmental exposures to the cancer.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 59 Years |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Centre Chirurgical Marie Lannelongue Academic / other |
| Locations | 3 sites (Le Plessis-Robinson and 2 other locations) |
| Status | Recruiting |
| Started | October 1, 2021 |
| Main results expected | October 1, 2022 |
| Study ends | February 1, 2027 |
| Registry record updated | May 6, 2026 |
| Trial ID | NCT05119244 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 to 59 treated for primary lung cancer at one of the participating hospitals who agree to participate are eligible.
✕Probably not a fit
People older than 59, those not treated at the listed hospitals, or those who do not consent would not be eligible and therefore would not benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project collects blood and hair samples from patients aged 18–59 treated for primary lung cancer at three French hospitals to measure markers of cannabis exposure and other environmental carcinogens. Samples will be analyzed to quantify toxic compounds and reconstruct exposure histories alongside clinical data. The work responds to mixed prior evidence: toxicology shows high concentrations of carcinogens in cannabis smoke while epidemiology has been largely reassuring. By adding biomarker data from treated patients, the study aims to clarify possible relationships between cannabis exposure and lung carcinogenesis.
Why it matters
Potential benefit: If successful, the study could improve understanding of whether cannabis exposure contributes to lung cancer and help guide prevention advice and patient counseling.
How similar studies have gone: Previous human studies have generally not shown a clear link between cannabis smoking and lung cancer while laboratory analyses find higher carcinogen concentrations in cannabis smoke, so human biomarker data remain limited and this approach is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Any patient from 18 y.o to 59 y.o treated in one of the three above-mentioned hospitals for primary lung cancer, whatever its stage, and agreeing to participate in this research. Exclusion Criteria: * Patient denied participation.
Where it's running
-
Centre Chirurgical Marie Lannelongue
Le Plessis-Robinson, France Recruiting -
Hopital Paris Saint Joseph
Paris, France Completed -
Institut Gustave Roussy
Villejuif, France Completed
Study contacts
- Study coordinator: Pauline PRADERE, MD
- Email: p.pradere@ghpsj.fr
- Phone: 01.40.94.22.79
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.