Enhancing cognitive performance using neurostimulation and biosensing technology
CAMSAN: Cognitive Augmentation Via Multimodal Sensing and Auricular Neurostimulation
NA · OpenBCI · NCT06782360
This study is testing if a new type of brain stimulation combined with a special headset can help healthy people think better while they do different tasks.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | OpenBCI (industry) |
| Locations | 1 site (Brooklyn, New York) |
| Trial ID | NCT06782360 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to improve cognitive performance in healthy volunteers by applying transcutaneous auricular neurostimulation (tAN) in conjunction with a biosensing headset. Participants will engage in various cognitive tasks while their cognitive states are monitored for stress, attention, and cybersickness. The study is structured in three phases: establishing a baseline cognitive state, evaluating the effects of manual tAN, and developing a closed-loop system that adjusts neurostimulation based on real-time biometric feedback. The effectiveness of active neurostimulation will be compared to a sham stimulation group to assess improvements in cognitive performance.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy individuals aged 18 to 55 who are right-hand dominant and proficient in English.
Not a fit: Patients with uncontrolled medical or psychiatric conditions, or those with a history of certain mental health disorders, may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to innovative methods for enhancing cognitive function and managing stress in various populations.
How similar studies have performed: While the use of neurostimulation for cognitive enhancement is an emerging field, this specific closed-loop approach has not been widely tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy human subjects between the ages of 18 and 55 * Normal color vision and near visual acuity of 20/30 without correction. * Participant is right-hand dominant * Proficient in the English language * Ability to understand the explanations and instructions given by the study personnel Exclusion Criteria: * Participant presents current evidence of an uncontrolled and/or clinically significant medical condition or psychiatric condition * Participant is participating in another interventional trial within 90 days prior to or throughout duration of trial * Participant has a prior diagnosis of post-traumatic stress disorder, acute stress disorder, or generalized anxiety disorder * Participant has a diagnosis of attention deficit hyperactivity disorder (ADHD) and/or is currently taking medications for the treatment of ADHD. * Current or recent history of substance abuse or drug dependence including nicotine and alcohol, or use of mind-altering drugs in the past 30 days. * Participant has abnormal ear anatomy, ear infection present, or ear piercing that could interfere with stimulation * Participant has a recent history of epileptic seizures; including photosensitive epilepsy * Participant has a recent history of neurologic diseases or traumatic brain injury * Participant has presence of implanted medical devices (e.g., pacemakers, cochlear prostheses, neurostimulators) * Females who are pregnant or lactating * Participant has any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants are risk because of participation in the trial, or may influence the result of the trial, or the participant's ability to participate in the trial * Sensitivity to bright screens or virtual reality displays * Recent history of neurological and psychiatric disease/disorder
Where this trial is running
Brooklyn, New York
- OpenBCI — Brooklyn, New York, United States (RECRUITING)
Study contacts
- Principal investigator: Musa Mahmood, PhD — OpenBCI
- Study coordinator: Musa Mahmood, PhD
- Email: musa@openbci.com
- Phone: 347-692-8870
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Healthy, Cognitive Change, Effects of External Neurostimulation on Cognition, cognitive performance, neurostimulation, stress, attention, cybersickness