Endoscopic removal of cancerous and precancerous lesions in the digestive tract
Retrospective Study of Efficacy and Safety of the Endoscopic Removal of Cancerous and Precancerous Lesions of the Upper and Lower Digestive Tract
This project looks back at adults who had endoscopic removal of upper or lower digestive tract tumors to see which resection techniques worked best and were safest.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Azienda USL Reggio Emilia - IRCCS Government |
| Locations | 1 site (Reggio Emilia, RE) |
| Trial ID | NCT04780256 on ClinicalTrials.gov |
What this trial studies
This is a retrospective review of endoscopic resection procedures performed for cancerous and precancerous lesions in the esophagus, stomach, duodenum, colon, and rectum. It compares outcomes and safety for techniques such as mucosal resection (en bloc and piecemeal), endoscopic submucosal dissection (ESD) and its variants, and full-thickness resection. Data will be drawn from procedures performed at a single center and will include procedural details, complication rates, and resection success metrics. The goal is to describe relative performance of different endoscopic approaches across anatomical sites.
Who should consider this trial
Good fit: Adults (18 years or older) who have undergone endoscopic resection of an upper or lower digestive tract tumor and can provide informed consent.
Not a fit: People younger than 18, those who have not had endoscopic resection, or those unable to provide informed consent are not eligible and would not benefit from participation.
Why it matters
Potential benefit: If successful, the findings could help doctors choose the safest and most effective endoscopic technique for removing early digestive tract tumors, potentially reducing complications and repeat procedures.
How similar studies have performed: Previous retrospective and prospective series have shown EMR and ESD can effectively remove early GI neoplasms with differing en bloc resection and complication rates, while full-thickness endoscopic techniques are newer and less extensively studied.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years or older * all patients who have undergone endoscopic resection of an upper or lower digestive tract tumor Exclusion Criteria: * age under 18 * inability to provide informed consent
Where this trial is running
Reggio Emilia, RE
- IRCCS-AUSL Reggio Emilia — Reggio Emilia, Re, Italy (Recruiting)
Study contacts
- Study coordinator: Paolo Cecinato, MD
- Email: paolo.cecinato@ausl.re.it
- Phone: +390522296111
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.