Clinical trial Recruiting at 1 site Observational Ages 18 to 100

Endoscopic removal of cancerous and precancerous lesions in the digestive tract

Official title: Retrospective Study of Efficacy and Safety of the Endoscopic Removal of Cancerous and Precancerous Lesions of the Upper and Lower Digestive Tract

Run by Azienda USL Reggio Emilia - IRCCS · NCT04780256 · Data updated 2026-11-12

This project looks back at adults who had endoscopic removal of upper or lower digestive tract tumors to see which resection techniques worked best and were safest.

More Esophageal Neoplasms trials

Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexAll
Enrollment2000 (estimated)
SponsorAzienda USL Reggio Emilia - IRCCS
Government
Locations1 site (Reggio Emilia, RE)
StatusRecruiting
StartedMarch 15, 2021
Main results expectedDecember 2025
Study endsDecember 2025
Registry record updatedOctober 3, 2025
Trial IDNCT04780256 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18 years or older) who have undergone endoscopic resection of an upper or lower digestive tract tumor and can provide informed consent.

Probably not a fit

People younger than 18, those who have not had endoscopic resection, or those unable to provide informed consent are not eligible and would not benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a retrospective review of endoscopic resection procedures performed for cancerous and precancerous lesions in the esophagus, stomach, duodenum, colon, and rectum. It compares outcomes and safety for techniques such as mucosal resection (en bloc and piecemeal), endoscopic submucosal dissection (ESD) and its variants, and full-thickness resection. Data will be drawn from procedures performed at a single center and will include procedural details, complication rates, and resection success metrics. The goal is to describe relative performance of different endoscopic approaches across anatomical sites.

Why it matters

Potential benefit: If successful, the findings could help doctors choose the safest and most effective endoscopic technique for removing early digestive tract tumors, potentially reducing complications and repeat procedures.

How similar studies have gone: Previous retrospective and prospective series have shown EMR and ESD can effectively remove early GI neoplasms with differing en bloc resection and complication rates, while full-thickness endoscopic techniques are newer and less extensively studied.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years or older
* all patients who have undergone endoscopic resection of an upper or lower digestive tract tumor

Exclusion Criteria:

* age under 18
* inability to provide informed consent

Where it's running

  • IRCCS-AUSL Reggio Emilia
    Reggio Emilia, Re, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.