Endoscopic removal of cancerous and precancerous lesions in the digestive tract
Official title: Retrospective Study of Efficacy and Safety of the Endoscopic Removal of Cancerous and Precancerous Lesions of the Upper and Lower Digestive Tract
Run by Azienda USL Reggio Emilia - IRCCS · NCT04780256 · Data updated 2026-11-12
This project looks back at adults who had endoscopic removal of upper or lower digestive tract tumors to see which resection techniques worked best and were safest.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Azienda USL Reggio Emilia - IRCCS Government |
| Locations | 1 site (Reggio Emilia, RE) |
| Status | Recruiting |
| Started | March 15, 2021 |
| Main results expected | December 2025 |
| Study ends | December 2025 |
| Registry record updated | October 3, 2025 |
| Trial ID | NCT04780256 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18 years or older) who have undergone endoscopic resection of an upper or lower digestive tract tumor and can provide informed consent.
✕Probably not a fit
People younger than 18, those who have not had endoscopic resection, or those unable to provide informed consent are not eligible and would not benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a retrospective review of endoscopic resection procedures performed for cancerous and precancerous lesions in the esophagus, stomach, duodenum, colon, and rectum. It compares outcomes and safety for techniques such as mucosal resection (en bloc and piecemeal), endoscopic submucosal dissection (ESD) and its variants, and full-thickness resection. Data will be drawn from procedures performed at a single center and will include procedural details, complication rates, and resection success metrics. The goal is to describe relative performance of different endoscopic approaches across anatomical sites.
Why it matters
Potential benefit: If successful, the findings could help doctors choose the safest and most effective endoscopic technique for removing early digestive tract tumors, potentially reducing complications and repeat procedures.
How similar studies have gone: Previous retrospective and prospective series have shown EMR and ESD can effectively remove early GI neoplasms with differing en bloc resection and complication rates, while full-thickness endoscopic techniques are newer and less extensively studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years or older * all patients who have undergone endoscopic resection of an upper or lower digestive tract tumor Exclusion Criteria: * age under 18 * inability to provide informed consent
Where it's running
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IRCCS-AUSL Reggio Emilia
Reggio Emilia, Re, Italy Recruiting
Study contacts
- Study coordinator: Paolo Cecinato, MD
- Email: paolo.cecinato@ausl.re.it
- Phone: +390522296111
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.