Endoscopic Features of the Upper GI Tract at High Altitude in Zaduo County
Official title: A Prospective Cohort Study on Endoscopic Features of Upper Gastrointestinal Tract at High Altitude --Zaduo County
Run by Jilin University · NCT07755384 · Data updated 2026-11-12
This observational study tests the endoscopic characteristics of reflux-related esophageal conditions in adults undergoing gastroscopy in Zaduo County, with matched comparisons from Jilin Province.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Jilin University Academic / other |
| Locations | 1 site (Yushu, Qinghai) |
| Status | Recruiting |
| Started | December 1, 2025 |
| Main results expected | October 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | August 10, 2026 |
| Trial ID | NCT07755384 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older living in Zaduo County for at least 6 months and scheduled for sedated gastroscopy.
✕Probably not a fit
Patients who do not have reflux-related esophageal findings or whose endoscopy is non-diagnostic may not receive direct benefit from the study results.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective observational study enrolls adults undergoing sedated gastroscopy at Zaduo County People's Hospital. It will compare endoscopic findings with matched cases from Jilin Province to characterize esophageal features associated with high-altitude living. The study focuses on reflux esophagitis and related conditions in the high-altitude population, considering factors such as hypoxia and Helicobacter pylori infection. Analysis will describe endoscopic patterns and may inform understanding of how altitude-related factors influence upper GI tract manifestations.
Why it matters
Potential benefit: If successful, findings could improve recognition and characterization of altitude-related esophageal conditions and guide local diagnostic considerations.
How similar studies have gone: Prior studies using endoscopy to characterize esophageal disease at high altitude are limited, making this approach relatively novel in this population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged ≥18 years; * Resided in Zaduo County for ≥6 months; * Undergoing painless (sedated) gastroscopy at our institution; * Absence of severe cardiopulmonary diseases or other conditions contraindicating gastroscopy; * Voluntary provision of written informed consent. Exclusion Criteria: * Emergency endoscopy; * History of partial or total esophagogastrectomy; * Planned endoscopic ultrasound (EUS) or endoscopic submucosal dissection (ESD); * Comorbidities including severe cardiac, hepatic, or renal dysfunction, or malignant tumors; * Pregnancy or lactation, chronic alcoholism, or psychiatric disorders precluding cooperation; * Participation in other interventional clinical trials within the recent past; * Age \<18 years; * Incomplete endoscopic examination (e.g., poor preparation, technical failure); * Any other condition deemed unsuitable for participation by the investigator.
Where it's running
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Zaduo County People's Hospital
Yushu, Qinghai, China Recruiting
Study contacts
- Principal investigator: Dong Yang, Doctor — Zaduo County People's Hospital
- Study coordinator: Rucai Li, Doctor
- Email: 1271025352@qq.com
- Phone: 86-18397118370
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.