Endoscopic assistance for anterior hyaloid peeling during keratoprosthesis surgery
Impact of Endoscopic Assisted Anterior Hyaloid Peeling in Boston Type 1 Keratoprosthesis in Reducing Postoperative Complications
This study is testing if using a special camera to help with a specific part of eye surgery can reduce complications and improve vision for people getting a Boston keratoprosthesis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Centre hospitalier de l'Université de Montréal (CHUM) Academic / other |
| Locations | 1 site (Montréal, Quebec) |
| Trial ID | NCT04337944 on ClinicalTrials.gov |
What this trial studies
This study investigates the use of endoscopic assistance for peeling the anterior hyaloid membrane during Boston keratoprosthesis type 1 surgery. The goal is to reduce postoperative complications such as retroprosthetic membrane formation and glaucoma progression. By performing pars plana vitrectomy (PPV) concurrently with keratoprosthesis surgery, the study aims to improve visual outcomes and decrease the incidence of complications. The methodology involves a complete PPV with endoscopic assistance to enhance visualization during the peeling process.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 80 who are suitable for both Boston keratoprosthesis and pars plana vitrectomy.
Not a fit: Patients who are not candidates for keratoprosthesis or those requiring repeat surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce vision loss and complications for patients undergoing keratoprosthesis surgery.
How similar studies have performed: Previous studies have shown that combined surgeries can reduce complications, suggesting this approach may be beneficial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged from 18 to 80 years old * Informed consent * Boston keratoprosthesis candidate * Pars plana vitrectomy candidate * Ability to be followed for the duration of the study Exclusion Criteria: * Aged less than 18 or more than 80 years old * Inability to give informed consent * Repeat Boston keratoprosthesis * Repeat pars plana vitrectomy
Where this trial is running
Montréal, Quebec
- Centre Hospitalier de l'Université de Montréal (CHUM) — Montréal, Quebec, Canada (Recruiting)
Study contacts
- Principal investigator: Mona Harissi-Dagher, MD — Centre hospitalier de l'Université de Montréal (CHUM)
- Study coordinator: Marie-Catherine Tessier, M.Sc.
- Email: marie-catherine.tessier.chum@ssss.gouv.qc.ca
- Phone: 1-514-890-8000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.