EMDR Toolbox to reduce psychological distress in people with early-stage cancer

Feasibility and Efficacy of an EMDR Psychotherapeutic Intervention With Additional Procedures (EMDR Toolbox Method) in Improving the Psychological Well-Being of Patients Diagnosed With Oncological Disease: A Randomized Study.

Not applicable Interventional Lega Cancro Ticino · NCT07481890

This trial will test whether the EMDR Toolbox therapy, compared with standard EMDR, can help adults with stage I–II cancer reduce psychological distress.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment46 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorLega Cancro Ticino Academic / other
Locations2 sites (Bellinzona, Canton Ticino and 1 other locations)
Trial IDNCT07481890 on ClinicalTrials.gov

What this trial studies

This interventional trial offers either standard EMDR or the EMDR Toolbox Method to adults with stage I–II cancer to test feasibility and effects on psychological distress. The program is delivered by trained clinicians within liaison psychology services and integrates routine distress screening with trauma-focused psychotherapy. Outcomes include measures of psychological distress, acceptability, and feasibility such as session completion and questionnaire return. Patients must be able to complete questionnaires and provide written informed consent, and those with psychiatric conditions that impair consent are excluded.

Who should consider this trial

Good fit: Adults aged 18–65 with stage I–II cancer who can complete questionnaires and provide informed consent are the intended participants.

Not a fit: Patients with severe psychiatric disorders that impair informed consent or those with more advanced cancer stages likely will not be eligible or benefit from this program.

Why it matters

Potential benefit: If successful, this could offer cancer patients a trauma-focused therapy that reduces psychological distress and improves coping during treatment.

How similar studies have performed: EMDR is an established treatment for trauma-related distress and small studies suggest benefits for cancer-related distress, but the specific EMDR Toolbox Method has been less extensively studied.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical stage of the tumor: Stage I, II (TNM classification)
* Age ≥ 18 years \<=65
* Conditions enabling correct implementation of the proposed program (ability to complete questionnaires)
* Written informed consent

Exclusion Criteria:

* Psychiatric or other disorders that may impair the ability to provide informed consent.

Where this trial is running

Bellinzona, Canton Ticino and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions CancerPsychological DistressEye Movement Desensitization and ReprocessingPsychosomaticsEMDR Toolbox MethodTrauma-focused psychotherapyPsychotherapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.