Elevating legs to reduce low blood pressure during anesthesia induction
Lower Extremity Elevation to Minimize Hemodynamic Instability During Induction of General Anesthesia - a Prospective Randomized Controlled Study
This study tests if raising patients' legs during anesthesia can help prevent low blood pressure and reduce the need for medications.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | The University of Texas Health Science Center, Houston Academic / other |
| Locations | 1 site (Houston, Texas) |
| Trial ID | NCT06513169 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate whether elevating the lower extremities can decrease the occurrence of post-induction hypotension in patients undergoing general anesthesia. It will compare the use of vasoactive medications in patients who receive lower extremity elevation versus those who do not. Additionally, the study will assess any changes in cardiac output associated with this intervention. The findings could provide insights into improving patient outcomes during anesthesia induction.
Who should consider this trial
Good fit: Ideal candidates include patients classified as ASA 3 or lower who require general anesthesia.
Not a fit: Patients with allergies to common anesthetic drugs, pregnant women, those requiring rapid sequence induction, prisoners, or those who refuse participation may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to fewer instances of low blood pressure during anesthesia, enhancing patient safety.
How similar studies have performed: While this specific approach is being tested, similar studies have shown promising results in managing hypotension during anesthesia.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * American Society of Anesthesiologists (ASA)3 or lower * Patients requiring general anesthesia Exclusion Criteria: * Allergic reaction to drugs commonly used for general anesthesia including fentanyl, midazolam, propofol, ephedrine and phenylephrine * Pregnant women * Requiring rapid sequence induction * Prisoners * Patient refusal * Emergency Surgery
Where this trial is running
Houston, Texas
- The University of Texas Health Science Center at Houston — Houston, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Ranganathan Govindaraj, MD — The University of Texas Health Science Center, Houston
- Study coordinator: Ranganathan Govindaraj, MD
- Email: Ranganathan.Govindaraj@uth.tmc.edu
- Phone: (713) 500-6200
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.