Electroacupuncture for menstrual pain from adenomyosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares real electroacupuncture with a sham electroacupuncture procedure in women who have moderate to severe dysmenorrhea due to adenomyosis. Eligible participants are adult women with at least three consecutive cycles of painful menstruation and stable menstrual timing. Participants will receive either electroacupuncture or a sham procedure and will be monitored for changes in pain intensity and for any adverse effects. The study focuses on both symptom relief and safety of the electroacupuncture approach.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Meeting the diagnosis criteria of dysmenorrhea secondary to adenomyosis.
* Female patients aged between 18 and 50.
* Dysmenorrhea lasting for 3 consecutive menstrual cycles or more.
* At least three consecutive menstrual cycles with an interval of 24 to 38 days, differing by less than 7 days, and menstrual periods lasting 2 to 8 days before screening.
* At least 2 days of worst pain score ≥4 on Numerical Rating Scale during the screening period.
* Having not used medications, other than rescue medicine, or therapies for dysmenorrhea secondary to adenomyosis for at least 1 month before randomization, and consenting not to use throughout the process of the research.
* Volunteering to participate the trial and signing written informed consent.

Exclusion Criteria:

* Diagnosed with Endometriosis or having a history of endometriosis-related surgery
* Currently taking hormonal medications, including: a.use of GnRH agonists within 6 months before the screening period; b. use of progestins or danazol and other long-acting hormones within 3 months before the screening period; c. use of oral contraceptive-like short-acting hormones within one month before the screening period;
* Having clinically significant gynecologic condition such as clinically significant endometrial pathology, persistent complex ovarian cyst larger than 3 cm or simple ovarian cyst larger than 5 cm, or single fibroid 4 cm or larger or more than 4 fibroids measuring at least 2 cm or symptomatic submucosal fibroid of any size.
* having an IUD.
* HB \< 90G/L.
* Having any other chronic pain syndrome that required chronic analgesic or other chronic therapy.
* Having a current history of undiagnosed abnormal genital bleeding.
* Malignant tumors (including the reproductive system and other systems).
* Combined with severe diseases in the cardiac, respiratory, renal, liver, and hematopoietic systems, psychiatric disorder and/or cognitive disorders.
* Pregnant, breast feeding, planning a pregnancy within the next 7 months.

Where it's running

• Guang'anmen Hospital, China Academy of Chinese Medical Sciences
  Beijing, China Recruiting

Study contacts

• Principal investigator: Zhishun Liu — Guang'anmen Hospital of China Academy of Chinese Medical Sciences
• Study coordinator: Zhishun Liu
• Email: zhishunjournal@163.com
• Phone: +861088002331

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Good pain consultation for endometriosis

  This trial will test whether adding a 'good pain consultation' with early biopsychosocial pain education to usual care helps biological women with endometriosis manage pain and improve quality of life.

  Recruiting Sorlandet Hospital HF · Kristiansand, Agder · NCT07205614

• Osteopathic Manipulative Treatment for Dysmenorrhea Symptoms

  This pilot study tests whether a targeted OMT session before the next period can reduce pain and other dysmenorrhea symptoms in female university community members.

  Recruiting Western University of Health Sciences · Pomona, California · NCT07849140

• Diaphragm-Pelvic Floor Training for Young Women with Menstrual Pain

  A randomized trial tests whether Diaphragm-Pelvic Floor Synergy training can reduce menstrual pain and improve quality of life in university-aged women with primary dysmenorrhea.

  Recruiting Riphah International University · Islamabad, Punjab Province · NCT07754305

• Cannabinoid-based product for gynecologic pain in endometriosis, adenomyosis, or PID

  This study tests a high-CBD, hemp-derived product against placebo in adults with gynecologic pain from endometriosis, adenomyosis, or PID over one week to see if it reduces pain and related symptoms.

  Recruiting Phase 1/2 Mclean Hospital · Belmont, Massachusetts · NCT07728695

• Samphire Guided Care for Wellbeing at Work

  This study tests a 12-week digital program with at-home neuromodulation to see if it helps women with menstrual or perimenopausal symptoms feel better at work and in daily life.

  Recruiting Samphire Group, Inc. · San Francisco, California · NCT07679074

• Aerobic Exercise vs. Jacobson’s Relaxation for Primary Dysmenorrhea

  This study tests whether aerobic exercise or Jacobson’s progressive relaxation can help reduce pain and fatigue and improve quality of life for young women with primary dysmenorrhea.

  Recruiting Riphah International University · Okāra, Punjab Province · NCT07628452

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.