Electrical Impedance Tomography for Monitoring Lung Disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will use Electrical Impedance Tomography (EIT) to record real-time, spatial patterns of lung ventilation in adults with a range of lung diseases and in healthy volunteers. Participants will undergo noninvasive EIT recordings alongside standard seated spirometry when possible, and a subgroup who cannot perform spirometry will be included to examine EIT utility without forced breathing. Investigators will compare EIT images with spirometry measures and normal reference data to identify ventilation patterns associated with different lung conditions. The work is conducted at the Department of Pulmonary Diseases and Tuberculosis, University Hospital Olomouc.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years and older
* Individuals diagnosed with any of the following lung diseases, as these are the primary focus of the study: Chronic obstructive pulmonary disease, Asthma, Pulmonary fibrosis, Pneumonia, Patients with a history of COVID-19 infection showing residual pulmonary findings.
* Additionally, healthy subjects will be enrolled to obtain normal standard values (with normal physical examination and no respiratory symptoms, BMI 18-36 - cause EIT performance can be BMI dependent, Non-smokers or ex-smokers abstinent ≥12 months)
* Ability to perform spirometry while seated, except for possible participants who are specifically part of a subgroup analysis where inability to perform spirometry is the condition which is studied.

Signing of an informed consent that has been approved by the ethics committee

Exclusion Criteria:

* Patients under 18 years of age
* Severe cardiovascular disease
* Pregnancy
* Inability to express consent
* Acute respiratory infection: Except for those recovering from pneumonia or COVID-19 within the study focus, participants with current respiratory infections will be excluded to avoid confounding effects on lung function tests
* Inability to perform spirometry

Where it's running

• Department of Pulmonary Diseases and Tuberculosis, University hospital Olomouc
  Olomouc, Czechia Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.