Clinical trial Recruiting at 1 site Interventional Ages 65 and up

Elastic-band exercises to build strength and lower depression in hospitalized older adults

Official title: Effects of Elastic Band Resistance Exercise on Muscle Strength and Depression in Hospitalized Elderly Patients.

Run by National Taiwan University · NCT06205147 · Data updated 2026-11-12

This program will test whether a five-day, low-resistance elastic band exercise routine can increase muscle mass and strength and reduce fear of falling and depression in hospitalized people aged 65 and older.

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Quick facts

Study typeInterventional
Ages65 Years and up
SexAll
Enrollment62 (estimated)
SponsorNational Taiwan University
Academic / other
Locations1 site (Taipei, Taiwan)
StatusRecruiting
StartedMarch 5, 2025
Main results expectedDecember 31, 2025
Study endsDecember 31, 2025
Registry record updatedJuly 24, 2025
Trial IDNCT06205147 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are hospitalized people aged 65 or older who can follow instructions, are expected to remain hospitalized more than seven days, and meet minimum limb strength and grip strength thresholds (≥3/5 limb strength and grip ≥26 kg for men or ≥18 kg for women).

Probably not a fit

Patients with unstable cardiac disease, poorly controlled blood pressure, acute neurological injuries, cognitive impairment or Alzheimer’s, long-term ventilator dependence, or very short hospital stays are unlikely to benefit or will be excluded.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Hospitalized adults aged 65 and older are randomized to either a five-day elastic band resistance program or usual care in a randomized controlled design. The intervention delivers two 20-minute low-resistance sessions per day for five days (200 minutes total) focusing on upper- and lower-limb exercises with elastic bands. Muscle mass and limb strength are measured with non-invasive instruments and grip strength recorded in kilograms, and participants complete questionnaires on fear of falling and geriatric depression. Enrollment requires the ability to follow instructions and an expected hospital stay longer than seven days, while patients with serious cardiac, neurological, or cognitive conditions are excluded.

Why it matters

Potential benefit: If successful, the program could help hospitalized older adults regain muscle mass and strength faster and reduce fear of falling and depressive symptoms.

How similar studies have gone: Previous outpatient and community elastic-band resistance programs have improved strength and mood in older adults, but intensive five-day programs in hospitalized patients have been less well tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age of 65 years or older.
2. Anticipated hospital stay exceeding 7 days.
3. Able to follow instructions.
4. Four-limb muscle strength of at least three points, and grip strength measurements with a minimum of 26 kilograms for males and 18 kilograms for females.

Exclusion Criteria:

1. This includes individuals with cardiovascular diseases such as acute myocardial infarction, unstable angina, poorly controlled arrhythmias, complete atrioventricular block, acute heart failure, acute myocarditis, acute pericarditis, and other cardiac conditions.
2. Poorly controlled hypertension, with systolic blood pressure less than 90 mmHg or greater than 200 mmHg under medication.
3. Individuals hospitalized due to acute neurological injuries or conditions, such as epilepsy, stroke, or Parkinson's disease.
4. Diagnosed with cognitive impairment or Alzheimer's disease.
5. Those who require long-term ventilator support and are unable to participate in the program.
6. Individuals with impaired consciousness who cannot cooperate.
7. A Glasgow Coma Scale score of less than 12, or inability to correctly answer questions about person, time, place, or follow instructions.

Where it's running

  • School of Nursing of National Taiwan University
    Taipei, Taiwan, Taiwan
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.