Effects of Yo-Yo Sleep on Heart and Metabolism

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates how alternating between short sleep during the week and longer sleep on weekends affects energy balance and cardiometabolic health in young-to-middle-aged adults. Participants will be assigned to one of three groups: those experiencing intermittent short sleep, those with social jetlag, and those maintaining adequate sleep. The study will last for four weeks and aims to determine whether a consistent sleep midpoint during short sleep periods leads to better health outcomes. The research addresses the real-life sleep patterns of many adults and their potential health implications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 18 to 49 years
* BMI 20-29.9 kg/m2
* Habitually sleeping 7-9 hours/night without sleep aids or naps

Exclusion Criteria:

* Sleep disorders
* Psychiatric disorders (including eating disorders) and seasonal affective disorder
* Pregnancy (current/prior year)
* Breastfeeding
* Smokers (Any cigarette smoking or ex-smokers \<3years)
* Diabetes
* Elevated blood pressure, taking beta-blockers
* Individuals taking anti-coagulants or anti-platelets
* Recent weight change or participation in a weight loss program or have ever had bariatric surgery or other weight loss or gastrointestinal procedure.
* Travel across time zones; shift work (non-traditional hours)

Where it's running

• Columbia University Irving Medical Center
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Marie-Pierre St-Onge, PhD — Columbia University
• Study coordinator: Marie-Pierre St-Onge, PhD
• Email: ms2554@cumc.columbia.edu
• Phone: 212-305-9549

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.