Effects of tDCS on cognitive function after Covid-19 infection

Effects of aTDCS Stimulation of the Dorsolateral Prefrontal Cortex on Cognitive Functions and the Parietal Memory Network, Default Mode Network in Patients Presenting Cognitive Symptoms After Covid-19 Infection: A Controlled Randomized Clinical Trial

Not applicable Interventional Istanbul Medipol University Hospital · NCT06183424

This study is testing if a brain stimulation treatment can help improve memory and thinking skills in people who have recently recovered from Covid-19.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years to 50 Years
SexAll
SponsorIstanbul Medipol University Hospital Academic / other
Locations1 site (Antalya)
Trial IDNCT06183424 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of bilateral transcranial direct current stimulation (tDCS) on cognitive functions, specifically memory and executive functions, in patients who have recently recovered from Covid-19. Participants will undergo tDCS targeting the dorsolateral prefrontal cortex while their brain connectivity will be assessed using resting-state fMRI to analyze alterations in the default mode network and parietal memory network. The goal is to understand how tDCS may improve cognitive complaints associated with Covid-19 recovery.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-50 who have recently tested positive for Covid-19 and have since recovered.

Not a fit: Patients with pre-existing neurological or psychiatric conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could enhance cognitive recovery in patients who have experienced cognitive deficits following Covid-19 infection.

How similar studies have performed: While the use of tDCS in cognitive rehabilitation is gaining interest, this specific application in post-Covid-19 patients is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Have received a positive value from the COVID-19 RT-PCR test in the last 60 days and turned negative
* Being between the ages of 18-50
* 21 days have passed since the disease onset date

Exclusion Criteria:

* Having any neurological or psychiatric disease

Where this trial is running

Antalya

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions COVID-19Covid-19tDCSCognitive function
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.