Effects of tart cherry powder on metabolic syndrome

Impact of 60 Days Powdered Tart Cherry Supplementation on Metabolic Syndrome

Not applicable Interventional Ohio University · NCT05614947

This study is testing whether taking tart cherry powder can help people with metabolic syndrome improve their heart health and reduce their risk of diabetes.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorOhio University Academic / other
Locations1 site (Athens, Ohio)
Trial IDNCT05614947 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of powdered tart cherry supplementation on individuals diagnosed with metabolic syndrome, a condition linked to increased risk of cardiovascular disease and type II diabetes. Participants will receive either the tart cherry supplement or a placebo over a 60-day period. The study aims to assess changes in metabolic parameters such as lipid levels, glucose clearance, and inflammation markers. By focusing on dietary interventions, the research seeks to explore the potential benefits of polyphenols found in tart cherries on metabolic health.

Who should consider this trial

Good fit: Ideal candidates are adults aged 25-60 who have been diagnosed with metabolic syndrome or meet its diagnostic criteria.

Not a fit: Patients currently taking medications for glucose or lipid control, or those with inflammatory conditions, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a natural dietary supplement option to help manage metabolic syndrome and reduce associated health risks.

How similar studies have performed: While the specific use of tart cherry supplementation is less common, other studies have shown positive effects of polyphenols on metabolic health, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Have been diagnosed with metabolic syndrome by a physician or meet the diagnostic criteria: Waist circumference greater than 40 inches (men) or greater than 35 inches (women), High blood pressure (greater than 130/80) or taking medication for high blood pressure, High triglycerides (greater than 150 mg/dL) or low HDL (less than 40 for men, less than 50 for women), High fasting blood glucose (100-126 mg/dL) or diagnosed as pre-diabetic
* Age 25-60

Exclusion Criteria:

* currently taking medication for glucose or lipid control, such as metformin and/or statin
* currently using anti-inflammatory medications \& have not used corticosteroids in the last two months
* diagnosed with or currently being treated for an inflammatory condition
* major organ system impairment (heart failure, renal failure, severe impairment of respiratory function)
* currently a smoker or quit less than 12 months ago

Where this trial is running

Athens, Ohio

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Metabolic Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.