Effects of TAP and QLB-1 blocks on pain management after laparoscopic surgery
A Comparison of the Effects of TAP (Transversus Abdominis Plane) Block and QLB-1 (Lateral Quadratum Lumbarum) Block on Postoperative Pain and Opioid Consumption in Laparoscopic Cholecystectomy
NA · Başakşehir Çam & Sakura City Hospital · NCT06663345
This study is testing if two different pain relief methods can help people having laparoscopic gallbladder surgery use less opioid medication and feel better after their operation.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 64 Years |
| Sex | All |
| Sponsor | Başakşehir Çam & Sakura City Hospital (other gov) |
| Locations | 1 site (Istanbul, Başakşehir) |
| Trial ID | NCT06663345 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of two regional anesthesia techniques, the Transversus Abdominis Plane (TAP) block and the Lateral Quadratum Lumborum (QLB-1) block, in reducing opioid consumption for patients undergoing laparoscopic cholecystectomy. The study aims to assess how these techniques can provide nonopioid analgesia and improve postoperative pain management. By comparing the outcomes of patients receiving these blocks, the trial seeks to enhance multimodal analgesia strategies in surgical settings.
Who should consider this trial
Good fit: Ideal candidates for this study are consenting adults aged 18 to 64 who are undergoing laparoscopic cholecystectomy and are classified as ASA-I or ASA-II.
Not a fit: Patients who may not benefit from this study include those with contraindications to regional anesthesia, chronic diseases, or those undergoing open abdominal surgery.
Why it matters
Potential benefit: If successful, this study could lead to reduced opioid consumption and improved pain management for patients after laparoscopic cholecystectomy.
How similar studies have performed: Previous studies have shown positive outcomes with regional anesthesia techniques like TAP blocks in managing postoperative pain, suggesting this approach is supported by existing literature.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * - Consenting patients, * He's having a laparoscopic cholecystectomy, * ASA-I-II, * Between the ages of 18 and 64, * No history of anticoagulant or antiaggregant drug use, * Regional anesthesia is not contraindicated and the anesthesiologist is deemed appropriate for regional anesthesia, * Under general anesthesia and undergoing laparoscopic surgery, * Oriented and cooperative patients, Exclusion Criteria: * - Patients without consent * Regional anesthesia is contraindicated, * He's having open abdominal surgery, * Not in the appropriate age range, * Chronic diseases such as uncontrolled DM and HT, * Drug allergy, * Taking anticoagulants or antiaggregants, * History of chronic analgesic use, * Presence of active infection in the area to be blocked, * Will not be able to comply with postoperative pain /VAS follow-up, * Patients with ASA-IV-V
Where this trial is running
Istanbul, Başakşehir
- Başakşehir Çam ve Sakura Şehir Hastanesi — Istanbul, Başakşehir, Turkey (RECRUITING)
Study contacts
- Principal investigator: Emine OZCAN — Başakşehir Çam & Sakura City Hospital
- Study coordinator: Emine OZCAN, MD
- Email: dr.emine3419@gmail.com
- Phone: +905301592856
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Postoperative Pain, TAP block, QLB-1 block, Nonopioid analgesia, postoperative pain, laparoscopic cholecystectomy