Effects of supplements on knee pain and inflammation

Effects of UC-II, Glucosamine and Curcumin Supplementation on Knee Pain and Inflammation: A Randomized, Single-blind, Placebo-controlled Parallel-group Trial

Not applicable Interventional Taipei Medical University · NCT06581094

This study tests whether taking supplements like UC-II, glucosamine, and curcumin can help people with osteoarthritis feel less knee pain and reduce inflammation.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment32 (estimated)
Ages20 Years to 70 Years
SexAll
SponsorTaipei Medical University Academic / other
Locations1 site (Taipei)
Trial IDNCT06581094 on ClinicalTrials.gov

What this trial studies

This research evaluates the impact of UC-II, glucosamine, and curcumin supplementation on chronic knee pain and inflammation. The study focuses on patients suffering from osteoarthritis, a condition characterized by joint pain and stiffness due to cartilage degradation. Participants will receive either the active supplements or a placebo to assess the effectiveness of these interventions in alleviating symptoms. The study aims to provide insights into alternative treatment options for managing knee pain associated with arthritis.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals experiencing chronic knee pain, particularly those diagnosed with osteoarthritis.

Not a fit: Patients with severe diseases of the heart, liver, kidneys, or other major health issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this could provide patients with a new, effective approach to managing knee pain and inflammation.

How similar studies have performed: Other studies have shown promising results with similar supplementation approaches for joint pain, indicating potential for success in this trial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Knee plain

Exclusion Criteria:

* Severe diseases of the heart, liver, kidneys, endocrine system, and other organs
* Long-term use of medication
* Infection, hypertension, diabetes, cerebrovascular disease, heart disease, liver disease, kidney disease, gastrointestinal disease
* Allergy to this product

Where this trial is running

Taipei

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions InflammationKnee Pain ChronicNon-denatured type II collagenGlucosamineCurcuminKnee Pain
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.